30134-13-5

Basic information

• Product Name: Ethanethioic acid, S-(3-phenylpropyl) ester
• CAS NO: 30134-13-5
• Molecular Formula: C11H14OS
• Molecular Weight: 194.298
• Mol File: 30134-13-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Ethanethioic acid, S-(3-phenylpropyl) ester(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanethioic acid, S-(3-phenylpropyl) ester(30134-13-5)
• EPA Substance Registry System: Ethanethioic acid, S-(3-phenylpropyl) ester(30134-13-5)

Safety Data

• Hazardous Substances Data: 30134-13-5(Hazardous Substances Data)

Upstream product

• 122-97-4 3-Phenyl-1-propanol 
• 10387-40-3 potassium thioacetate 
• 114764-11-3 3-phenylpropyl 2-(trimethylsilyl)ethyl sulfide 
• 75-36-5 acetyl chloride 
• 4119-41-9 1-iodo-3-phenylpropan 

Downstream Products

• 24734-68-7 3-Phenylpropane-1-thiol 

Relevant articles and documents

One-Pot Deoxygenation and Substitution of Alcohols Mediated by Sulfuryl Fluoride

Sulfuryl fluoride is a valuable reagent for the one-pot activation and derivatization of aliphatic alcohols, but the highly reactive alkyl fluorosulfate intermediates limit both the types of reactions that can be accessed as well as the scope. Herein, we report the SO2F2-mediated alcohol substitution and deoxygenation method that relies on the conversion of fluorosulfates to alkyl halide intermediates. This strategy allows the expansion of SO2F2-mediated one-pot processes to include radical reactions, where the alkyl halides can also be exploited in the one-pot deoxygenation of primary alcohols under mild conditions (52-95% yield). This strategy can also enhance the scope of substitutions to nucleophiles that are previously incompatible with one-pot SO2F2-mediated alcohol activation and enables substitution of primary and secondary alcohols in 54-95% yield. Chiral secondary alcohols undergo a highly stereospecific (90-98% ee) double nucleophilic displacement with an overall retention of configuration.