30152-05-7

Usage

Uses

Used in Pharmaceutical Synthesis:
Ethanone, 1-(3-hydroxy-4-pyridinyl)(9CI) is used as an intermediate in the synthesis of various pharmaceuticals. Its unique structure and functional groups make it a valuable building block for the development of new drugs with potential therapeutic applications.
Used in Agrochemical Synthesis:
Ethanone, 1-(3-hydroxy-4-pyridinyl)(9CI) is also utilized in the synthesis of agrochemicals, which are chemicals used in agriculture to enhance crop yield and protect plants from pests and diseases. Its presence in agrochemicals can contribute to the development of more effective and environmentally friendly products.
Used in Organic Chemistry Research:
Ethanone, 1-(3-hydroxy-4-pyridinyl)(9CI) is employed as a research tool in organic chemistry, where it can be used to study various chemical reactions and mechanisms. Its unique properties and reactivity make it a valuable compound for understanding and advancing the field of organic chemistry.
Used in Drug Development:
Due to its biological activity, Ethanone, 1-(3-hydroxy-4-pyridinyl)(9CI) may have potential applications in the development of new drugs. Its unique structure and functional groups can be exploited to design and synthesize novel therapeutic agents with improved efficacy and selectivity.
Used in Chemical Education:
Ethanone, 1-(3-hydroxy-4-pyridinyl)(9CI) can also be used in chemical education to teach students about the properties and reactions of ketones, as well as the importance of handling chemicals with care due to their potential hazards and toxicity.

Upstream product

• 15031-12-6 5-ethoxyoxazole 
• 78-94-4 methyl vinyl ketone 
• 1089689-12-2 1-(3-(methoxymethoxy)pyridin-4-yl)ethanone 
• 1089707-46-9 1-(3-(methoxymethoxy)pyridin-4-yl)ethanol 
• 81245-25-2 3-(methoxymethoxy)pyridine 
• 109-00-2 3-HYDROXYPYRIDINE 
• 83431-02-1 1-(3-methoxypyridin-4-yl)-ethanone 
• 59786-32-2 methyl 3-methoxy-4-pyridinecarboxylate 

Relevant academic research and scientific papers

CONDENSED TRICYCLIC COMPOUNDS AS PROTEIN KINASE INHIBITORS

There is provided compounds of formula I, (I) wherein R1, R2, R3 R4, R5, R6, R7a and R7b have meanings given in the description, and pharmaceutically-acceptable esters, amides, solvates or salts thereof, which compounds are useful in the treatment of diseases in which inhibition of a protein or lipid kinase (e.g. CDK8 and/or Haspin kinase) is desired and/or required, and particularly in the treatment of cancer or a proliferative disease.

AMINONITRILES AS KYNURENINE PATHWAY INHIBITORS

The present application provides novel kynurenine pathway inhibitors and pharmaceutically acceptable salts and prodrugs thereof. Also provided are methods for preparing these compounds. These compounds are useful in regulating the kynurenine pathway and the activity of indoleamine 2,3-dioxygenase and/or tryptophan 2,3-dioxygenase by administering a therapeutically effective amount of one or more of the compounds of formula (I) to a patient. By doing so, these compounds are effective in treating conditions associated with the dysregulation of the kynurenine pathway. A variety of conditions can be treated using these compounds and include diseases which are characterized by immunosuppression, abnormal cellular proliferation and/or inflammation. In one embodiment, the disease is cancer. In another embodiment, the disease is a viral infection. In a further embodiment, the disease is depression.

Oxazoles in Diels-Alder Reactions. Transformation of The Adducts to Either Pyridines or Pyrroles

The cycloadducts between acrylic acid or acrylonitrile and 5-ethoxyoxazoles are converted as formed to 3-hydroxypyridines.The Diels-Alder adducts from ethyl acrylate, or methyl or phenyl vinyl ketone can be isolated.In ethanolic HCl the adducts are transformed into 3-hydroxypyridines; in aqueous HCl the products are acylpyrrole analogues.A 4-substituent in the oxazole affects the reaction. 4-Methyl-5-ethoxyoxazole reacts much faster than its 5-ethylthio analogue.

AZABENZOXAZOLES: SYNTHESIS OF 3-METHYLISOXAZOLO- AND 2-METHYLOXAZOLOPYRIDINES

A convenient synthesis of 4-acetyl-3-hydroxypyridine is reported; this compound allows the preparation of the new isoxazolo- and oxazolopyridine ring systems.