3016-84-0Relevant academic research and scientific papers
A Class of N-O-Type Oxidants to Access High-Valent Palladium Species
Nappi, Manuel,Gaunt, Matthew J.
, p. 143 - 148 (2018/12/11)
This article presents a new class of mild reagents that is capable of oxidizing palladacycle(II) complexes to high-valent palladium species, promoting the formation of C-N bonds in stoichiometric and catalytic conditions. The weak N-O bond and the extremely electron-withdrawing benzenesulfonate group on the oxygen atom of the oxidant are crucial moieties to ensure the desired activity. The oxidation mechanism could involve outer-sphere single-electron transfer processes, opening the possibility for a complementary reactivity of Pd(IV) species.
N-heterocyclic carbene-catalyzed radical reactions for highly enantioselective β-hydroxylation of enals
Zhang, Yuexia,Du, Yu,Huang, Zhijian,Xu, Jianfeng,Wu, Xingxing,Wang, Yuhuang,Wang, Ming,Yang, Song,Webster, Richard D.,Chi, Yonggui Robin
supporting information, p. 2416 - 2419 (2015/03/04)
An N-heterocyclic carbene-catalyzed β-hydroxylation of enals is developed. The reaction goes through a pathway involving multiple radical intermediates, as supported by experimental observations. This oxidative single-electron-transfer reaction allows for highly enantioselective access to β-hydroxyl esters that are widely found in natural products and bioactive molecules.
