301693-64-1Relevant academic research and scientific papers
A facile one-pot synthesis of 4,5-diaryl-2,2-dimethyl-3(2H)-furanones
Lee, Ki-Wha,Choi, Young Hoon,Joo, Yung Hyup,Kim, Jin Kwan,Shin, Song Seok,Byun, Young Joo,Kim, Yeonjoon,Chung, Shin
, p. 1137 - 1142 (2002)
An efficient and practical one-pot synthesis of 4,5-diaryl-2,2-dimethyl-3(2H)-furanones has been achieved from 1,2-diarylethanones and 2-bromoisobutyryl cyanide in the presence of excess base, by employing the 'hard soft acid base' principle. The reaction scope of 2-bromoisobutyryl cyanide could be expanded to prepare a variety of 2,2-dimethyl-3(2H)-furanone derivatives other than 4,5-diaryl-2,2-dimethyl-3(2H)-furanones. Copyright
