55106-47-3

Upstream product

• 7677-24-9 trimethylsilyl cyanide 
• 20769-85-1 2-bromoisobutyric acid bromide 
• 20469-89-0 2-bromo-2-methylpropionyl chloride 
• 3252-43-5 dibromoacetonitrile 
• 67-64-1 acetone 

Downstream Products

• 301693-60-7 2,2-dimethyl-4-(4-methoxyphenyl)-5-[4-(methylthio)phenyl]-3(2H)-furanone 
• 301695-03-4 2,2-dimethyl-5-{3-fluoro-4-(methylthio)phenyl}-4-phenyl-3(2H)-furanone 
• 301695-58-9 2,2-dimethyl-5-{2-fluoro-4-(methylthio)phenyl}-4-phenyl-3(2H)furanone 
• 301695-07-8 4-(3-Chlorophenyl)-2,2-dimethyl-5-{3-fluoro-4-(methylthio)phenyl}-3(2H)-furanone 
• 301695-60-3 4-(3-Chlorophenyl)-2,2-dimethyl-5-{2-fluoro-4-(methylthio)phenyl}-3(2H)-furanone 
• 301697-12-1 2,2-Dimethyl-5-{3-fluoro-4-(methylthio)phenyl}-4-(3-fluorophenyl)-3(2H)-furanone 
• 301695-62-5 2,2-Dimethyl-5-{2-fluoro-4-(methylthio)phenyl}-4-(3-fluorophenyl)-3(2H)-furanone 
• 301695-10-3 4-(3,5-Difluorophenyl)-2,2-dimethyl-5-{3-fluoro-4-(methylthio)phenyl}-3(2H)-furanone 
• 301695-65-8 4-(3,5-Difluorophenyl)-2,2-dimethyl-5-{2-fluoro-4-(methylthio)phenyl}-3(2H)-furanone 
• 1202376-37-1 5-(4-(benzyloxy)phenyl)-4-(4-methoxyphenyl)-2,2-dimethylfuran-3(2H)-one 
• 1202368-40-8 5-(4-methoxyphenyl)-2,2-dimethyl-4-(4-(quinolin-2-ylmethoxy)phenyl)furan-3(2H)-one 
• 301695-82-9 5-{3-bromo-4-(methylthio)phenyl}-2,2-dimethyl-4-phenyl-3(2H)-furanone 
• 301696-30-0 5-{2-chloro-4-(methylthio)phenyl}-2,2-dimethyl-4-phenyl-3(2H)-furanone 
• 301696-20-8 2,2-dimethyl-4-(3-fluorophenyl)-5-{3-methyl-4-(methylthio)phenyl}-3(2H)-furanone 

Relevant academic research and scientific papers

1, 2 DISUBSTITUTED HETEROCYCLIC COMPOUNDS

1,2-disubstituted heterocyclic compounds which are inhibitors of phosphodiesterase 10 are described. Also described are processes, pharmaceutical compositions, pharmaceutical preparations and pharmaceutical use of the compounds in the treatment of mammals, including human(s) for central nervous system (CNS) disorders and other disorders which may affect CNS function. Among the disorders which may be treated are neurological, neurodegenerative and psychiatric disorders including, but not limited to, those associated with cognitive deficits or schizophrenic symptoms.