30225-76-4

Basic information

• Product Name: 3,4,5-trimethoxyphenyl formate
• Synonyms: 3,4,5-trimethoxyphenyl formate
• CAS NO: 30225-76-4
• Molecular Weight: 212.202
• Mol File: 30225-76-4.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 3,4,5-trimethoxyphenyl formate(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4,5-trimethoxyphenyl formate(30225-76-4)
• EPA Substance Registry System: 3,4,5-trimethoxyphenyl formate(30225-76-4)

Safety Data

• Hazardous Substances Data: 30225-76-4(Hazardous Substances Data)

Upstream product

• 86-81-7 3,4,5-trimethoxy-benzaldehyde 
• 64-18-6 formic acid 

Downstream Products

• 1354708-21-6 1-(4'-decyl-2'-hydroxyphenyl)-2-methoxy-3-(2'',3'',4'',6''-tetramethoxyphenyl)propane-1,3-dione 
• 1354708-27-2 7-decyl-3,2',3',4',6'-pentamethoxyflavone 
• 5333-45-9 1,2,3,5-tetramethoxybenzene 
• 6342-81-0 2,3,4,6-tetramethoxybenzoic acid 
• 832-65-5 2-hydroxy-4,5,6-trimethoxybenzaldehyde 
• 1240172-54-6 5,6,7-trimethoxy-3-(4-methoxyphenyl)-2H-chromen-2-one 
• 1394906-87-6 (R)-1-(tert-butylamino)-3-(3,4,5-trimethoxyphenoxy)propan-2-ol 
• 642-71-7 3,4,5-trimethoxyphenol 

Relevant articles and documents

Synthesis of polyalkoxy-3-(4-methoxyphenyl)coumarins with antimitotic activity from plant allylpolyalkoxybenzenes

Novel polyalkoxy-3-(4-methoxyphenyl)coumarins - analogues of natural antimitotic compounds - were synthesized from plant allylpolyalkoxybenzenes and tested in vivo in the phenotypic sea urchin embryo assay for antiproliferative antitubulin activity.

Enantioselective α-hydroxylation of β-keto esters catalyzed by chiral S-timolol derivatives

A screen of aryloxy aminopropanol organocatalysts derived from the β-blocker inhibitor S-timolol determined the most active catalyst of asymmetric α-hydroxylation of β-keto esters. (R)-1-(tert-butylamino)- 3-(3,4,5-trimethoxyphenoxy) propan-2-ol (3k) was the most effective derivative, enantioselectively catalyzing α-hydroxylation of β-keto esters using tert-butyl hydroperoxide as the oxidant in hexane to afford the corresponding products in excellent yield and with good enantioselectivity (up to 96% yield, 88% ee).

Selenoxides as catalysts for epoxidation and Baeyer-Villiger oxidation with hydrogen peroxide

Aryl benzyl selenoxides are catalysts for the epoxidation of various olefinic substrates and the Baeyer-Villiger oxidation of aldehydes and ketones with H2O2 in CH2Cl2 at 2.5 mol% catalyst. Benzyl 3,5-bis(trifluoromethyl)phenyl selenoxide (4) was the most effective catalyst while 2-(dimethylamino)phenyl benzyl selenoxide was the least. Mono-, di-, and trisubstituted alkenes were epoxidized and adamantanone, cyclohexanone, and 3,4,5-trimethoxybenzaldehyde underwent Baeyer-Villiger oxidation using 4 and H2O2. Competition studies showed that epoxidation reactions were faster than Baeyer-Villiger oxidations although the selectivity varied only from 1.3:1 to 4.6:1. Georg Thieme Verlag Stuttgart.