302331-95-9Relevant academic research and scientific papers
An efficient synthesis of β-C-glycosides based on the conformational restriction strategy: Lewis acid promoted silane reduction of the anomeric position with complete stereoselectivity
Terauchi, Masaru,Abe, Hiroshi,Matsuda, Akira,Shuto, Satoshi
, p. 3751 - 3754 (2007/10/03)
(Chemical Equation Presented) The reduction of glyconolactols having an anomeric carbon substituent by Et3SiH/TMSOTf proceeded with complete stereoselectivity to produce the corresponding β-C-glycosides when the substrates were conformationally restricted in the 4C 1-chair form by a 3,4-O-cyclic diketal or a 4,6-O-benzylidene protecting group. Thus, the efficient construction of β-C-glycosides was achieved on the basis of the conformation restriction strategy.
Spirophostins: Conformationally restricted analogues of adenophostin A
De Kort, Martin,Regenbogen, Anouk D.,Valentijn, A. Rob P. M.,Challiss, R. A. John,Iwata, Yoriko,Miyamoto, Shuichi,Van Der Marel, Gijs A.,Van Boom, Jacques H.
, p. 2696 - 2704 (2007/10/03)
The synthesis, biological evaluation, and molecular modeling of two conformationally restricted analogues of adenophostin A (1), denominated as spirophostin (3R)-10 and (3S)-11, as novel ligands for the D-myo-inositol 1,4,5-trisphosphate receptor (IP
