302335-76-8

Upstream product

• 302335-75-7 methyl 5-O-benzoyl-2-deoxy-α/β-L-xylofuranoside 
• 302349-32-2 (2S,3S)-2-(hydroxymethyl)-5-methoxytetrahydrofuran-3-ol 
• 98-88-4 benzoyl chloride 

Downstream Products

• 207128-22-1 β-2',3'-dideoxy-3'-fluoro-L-uridine 
• 178374-44-2 α-2',3'-dideoxy-3'-fluoro-L-uridine 
• 177365-14-9 β-L-2',3'-dideoxy-3'-fluorocytidine 
• 177365-14-9 2',3'-dideoxy-3'-fluoro-α-L-cytidine 

Relevant academic research and scientific papers

Synthesis of 2',3'-dideoxy-3'-fluoro-L-ribonucleosides as potential antiviral agents from D-sorbitol

2',3'-Dideoxy-3'-fluoro-L-ribonucleosides were synthesized as potential antiviral agents. The key intermediate, methyl 5-O-benzoyl-2-3-dideoxy-3-fluoro-L-ribofuranoside, which was prepared from D-sorbitol, was condensed with pyrimidine and purine bases to obtain the respective nucleosides. Among them, the cytosine analogue 2',3'-dideoxy-3'-fluoro-α-L-cytidine showed a moderate anti-HBV activity. (C) 2000 Elsevier Science Ltd.