207128-22-1

Upstream product

• 207128-21-0 1-((2S,4R,5S)-4-Fluoro-5-trityloxymethyl-tetrahydro-furan-2-yl)-1H-pyrimidine-2,4-dione 
• 73416-11-2 bis-trimethylsilyluracil 
• 302335-76-8 methyl 5-O-benzoyl-2,3-dideoxy-3-fluoro-α/β-L-ribofuranoside 
• 302349-32-2 (2S,3S)-2-(hydroxymethyl)-5-methoxytetrahydrofuran-3-ol 
• 816429-66-0 5'-O-trityl-2'-deoxy-L-uridine 
• 207128-18-5 1-((2S,4S,5S)-4-Hydroxy-5-trityloxymethyl-tetrahydro-furan-2-yl)-1H-pyrimidine-2,4-dione 
• 951-78-0 L-Deoxyuridine 
• 207128-16-3 Methanesulfonic acid (2S,3R,5S)-5-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-2-trityloxymethyl-tetrahydro-furan-3-yl ester 
• 302335-75-7 methyl 5-O-benzoyl-2-deoxy-α/β-L-xylofuranoside 

Downstream Products

• 177365-14-9 β-L-2',3'-dideoxy-3'-fluorocytidine 

Relevant academic research and scientific papers

Newly synthesized L-enantiomers of 3'-fluoro-modified β-2'- deoxyribonucleoside 5'-triphosphates inhibit hepatitis B DNA polymerases but not the five cellular DNA polymerases α, β, Γ, δ, and ε nor HIV-1 reverse transcriptase

Novel β-L-2',3'-dideoxy-3'-fluoro nucleosides were synthesized and further converted to their 5'-triphosphates. Their inhibitory activities against hepatitis B virus (HBV) and duck hepatitis B virus (DHBV) DNA polymerases, α, ?, γ, δ and ε were investigat

Synthesis of 2',3'-dideoxy-3'-fluoro-L-ribonucleosides as potential antiviral agents from D-sorbitol

2',3'-Dideoxy-3'-fluoro-L-ribonucleosides were synthesized as potential antiviral agents. The key intermediate, methyl 5-O-benzoyl-2-3-dideoxy-3-fluoro-L-ribofuranoside, which was prepared from D-sorbitol, was condensed with pyrimidine and purine bases to obtain the respective nucleosides. Among them, the cytosine analogue 2',3'-dideoxy-3'-fluoro-α-L-cytidine showed a moderate anti-HBV activity. (C) 2000 Elsevier Science Ltd.