302582-11-2Relevant articles and documents
Stereoselective synthesis of α-aminonitriles at non-anomeric positions of monosaccharides
Postel,Van Nhien,Pillon,Villa,Ronco
, p. 6403 - 6406 (2000)
α-Aminonitriles have been stereoselectively introduced at non-anomeric positions of monosaccharides, in which the carbon C-α is one of the atoms of the sugar ring. Target compounds were prepared from various ulose derivatives and amines using titanium(IV) isopropoxide as a mild and effective Lewis acid. (C) 2000 Elsevier Science Ltd.
First synthesis and evaluation of the inhibitory effects of Aza analogues of TSAO on HIV-1 replication
Van Nhien, Albert Nguyen,Tomassi, Cyrille,Len, Christophe,Marco-Contelles, José Luis,Balzarini, Jan,Pannecouque, Christophe,De Clercq, Erik,Postel, Denis
, p. 4276 - 4284 (2007/10/03)
Aza TSAO-T derivatives bearing a dihydroisothiazole dioxide ring instead of an oxathiole dioxide ring at the C-3′ position on the sugar moiety were prepared. We have synthesized four families of compounds depending on substitution at both N-3 and N-2″. Bi
Synthesis of 4-Amino-5-H-2,3-dihydroisothiazole-1,1-dioxide Ring Systems on Sugar Templates via Carbanion-Mediated Sulfonamide Intramolecular Cyclization Reactions (CSIC Protocols) of Glyco-α-sulfonamidonitriles
Dominguez, Laura,Van Nhien, Albert Nguyen,Tomassi, Cyrille,Len, Christophe,Postel, Denis,Marco-Contelles, Jose
, p. 843 - 856 (2007/10/03)
The carbanion-mediated sulfonate intramolecular cyclizations (CSIC protocols) of glyco-α-sulfona-midonitriles derived from readily available monosaccharides have been extensively investigated using potassium carbonate, cesium carbonate, n-BuLi, and LDA as