303111-00-4

Upstream product

• 183593-80-8 3-(4-bromo-phenyl)-3-phenyl-acrylic acid ethyl ester 
• 90-90-4 (4-bromophenyl)(phenyl)methanone 
• 183593-81-9 (Z)-3-(4-bromo-phenyl)-3-phenyl-acrylic acid ethyl ester 

Downstream Products

• 303111-01-5 (Z)-3-(4-furan-2-yl-phenyl)-3-phenyl-prop-2-en-1-ol 
• 303110-74-9 (Z)-(2S)-3-{4-[3-(4-Bromophenyl)-3-phenyl-allyloxy]-phenyl}-2-ethoxy-propionic acid ethyl ester 
• 303110-80-7 (Z)-(2S)-2-Ethoxy-3-{4-[3-(4-furan-2-yl-phenyl)-3-phenyl-allyloxy]-phenyl}-propionic acid ethyl ester 
• 494865-38-2 (Z)-{4-[3-(4-Bromo-phenyl)-3-phenyl-allyloxy]-phenyl}-acetic acid methyl ester 

Relevant academic research and scientific papers

Design and synthesis of novel PPARα/γ/δ triple activators using a known PPARα/γ dual activator as structural template

Using a known dual PPARα/γ activator (5) as a structural template, SAR evaluations led to the identification of triple PPARα/γ/δ activators (18-20) with equal potency and efficacy on all three receptors. These compounds could become useful tools for studying the combined biological effects of PPARα/γ/δ activation.

Novel compounds, their preparation and use

Novel compounds of the general formula (I), the use of these compounds as pharmaceutical compositions, pharmaceutical compositions comprising the compounds and methods of treatment employing these compounds and compositions. The present compounds may be u