303123-99-1Relevant articles and documents
Chiral Acetals as Stereoinductors: Diastereoface Selective Alkylation of Dihydrobenzoxazine-Derived Amide Enolates
Mulzer, Johann,Langer, Oliver,Hiersemann, Martin,Bats, Jan W.,Buschmann, Juergen,Luger, Peter
, p. 6540 - 6546 (2000)
Novel dihydrobenzoxazine-derived acetals of type 3 have been developed for asymmetric C-alkylations of propionyl amide enolates. High stereoselectivities are obtained for amides 15 and 22 which are rationalized in terms of intramolecular metal chelate formation.