30315-46-9

Usage

Uses

Used in Pharmaceutical Industry:
(S)-3-tert-Butylamino-1,2-propanediol is used as a chiral building block for the synthesis of various pharmaceutical compounds. Its unique structure allows for the creation of enantiomerically pure drugs, which can have different biological activities and reduce potential side effects.
Used in Drug Development:
(S)-3-tert-Butylamino-1,2-propanediol is used as a key intermediate in the development of new drugs. Its chiral nature enables the production of single-enantiomer drugs, which can offer improved efficacy and safety profiles compared to racemic mixtures.
Used in Chiral Synthesis:
(S)-3-tert-Butylamino-1,2-propanediol is used as a chiral auxiliary in asymmetric synthesis, facilitating the production of enantiomerically enriched compounds. This is crucial for the development of drugs with specific biological activities and reduced side effects.
Used in Research and Development:
(S)-3-tert-Butylamino-1,2-propanediol is utilized in research and development for the exploration of new chemical reactions and the synthesis of novel compounds with potential applications in various fields, including medicine, agriculture, and materials science.

InChI:InChI=1/C7H17NO2/c1-7(2,3)8-4-6(10)5-9/h6,8-10H,4-5H2,1-3H3/p+1/t6-/m0/s1

Upstream product

• 68430-32-0 [2S]-O-isopropylidene-3-tert-butylamino-1,2-propanediol 
• 453-17-8 D-Glyceraldehyde 
• 75-64-9 tert-butylamine 
• 687627-65-2 Terephthalic acid bis-((S)-3-tert-butylamino-2-hydroxy-propyl) ester 
• 15186-48-8 2,3-isopropylidene-glyceraldehyde 

Downstream Products

• 60559-92-4 (S)-2-(3-tert-butylamino-2-hydroxypropoxy)-3-cyanopyridine hydrochloride 
• 194861-99-9 ((2Ξ,5S)-3-tert-butyl-2-phenyl-oxazolidin-5-yl)-methanol 
• 30315-49-2 3-tert-butyl-2-phenyl-5-hydroxymethyloxazolidine 
• 26839-75-8 timolol 
• 59697-06-2 3-tert-butylamino-2-(4-morpholin-4-yl-[1,2,5]thiadiazol-3-yloxy)-propan-1-ol 

Relevant academic research and scientific papers

(4S)-4-tert-Butylaminomethyl-2-Phenyl-1,3-Dioxolanes, the By-Products in the Synthesis of (5S)-2-Phenyl-3-terf-Butyl-5-Hydroxymethyloxazolidines

Condensation of (S)-(-)-3-tert-butylamino-1,2-propanediol with benzaldehyde in the presence of benzoic acid yielded predominantly (2S,4S)- and (2R,4S)-2-phenyl-4-tert-butylaminomethyl-1,3-dioxolanes along with the usual reaction products, (5S)-2-phenyl-3-tert-butyl-5-hydroxymethyloxazolidines.

1-SUBSTITUTED AMINO-3-THIENO-[3,2-c]PYRIDINYLOXY-2-PROPANOLS

This invention provides new compounds of formula I, STR1 wherein X is sulphur or oxygen,R is alkyl of 3 to 7 carbon atoms or cycloalkyl of 3 to 7 carbon atoms, cycloalkyl of 3 to 7 carbon atoms monosubstituted by alkyl of 1 to 4 carbon atoms, α-dialkylpropinyl of 5 to 9 carbon atoms or α-dialkyl-allyl of 5 to 9 carbon atoms, hydroxyalkyl of 2 to 7 carbon atoms or phenoxyalkyl of 8 to 11 carbon atoms, the oxygen atom of the last two radicals being separated by at least two carbon atoms from the nitrogen atom to which R is bound, R 1 isI. hydrogen or alkyl of 1 to 4 carbon atoms in the 2,3,6 or 7 position, orIi. chlorine or bromine, in the 2, 3 or 7 position,Iii. nitro or--NHA wherein A is alkanoyl of 1 to 4 carbon atoms, in the 2, 3 or 7 position, orIv. fluorine, cyano or COOB, wherein B is alkyl of 1 to 4 carbon atoms, in the 2 or 3 position, andR 2 isI. hydrogen or alkyl of 1 to 4 carbon atoms in the 2, 3, 6 or 7 position,Ii. chlorine or bromine, in the 2, 3 or 7 position, orIii. fluorine in the 2 or 3 position,Useful in the treatment of heart diseases.