303153-12-0

Basic information

• Product Name: Acetic acid, (chlorosulfonyl)-, 1-methylethyl ester
• Synonyms: isopropyl chlorosulfonacetate;isopropyl chlorosulfonylacetate
• CAS NO: 303153-12-0
• Molecular Formula: C5H9ClO4S
• Molecular Weight: 200.643
• Mol File: 303153-12-0.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 253.0±23.0 °C(Predicted)
• Density: 1.361±0.06 g/cm3(Predicted)
• CAS DataBase Reference: Acetic acid, (chlorosulfonyl)-, 1-methylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Acetic acid, (chlorosulfonyl)-, 1-methylethyl ester(303153-12-0)
• EPA Substance Registry System: Acetic acid, (chlorosulfonyl)-, 1-methylethyl ester(303153-12-0)

Safety Data

• Hazardous Substances Data: 303153-12-0(Hazardous Substances Data)

Upstream product

• 56146-83-9 chlorosulfonyl-acetic acid methyl ester 
• 67-63-0 isopropyl alcohol 
• 4025-77-8 chlorosulfonylacetyl chloride 

Downstream Products

• 771584-89-5 isopropyl ({[(2E)-3-(3-cyanophenyl)prop-2-en-1-yl][4-(4-methyl-1,4-diazepan-1-yl)phenyl]amino}sulfonyl)acetate 
• 1492047-44-5 2-{[(isopropoxy-2-oxoethyl)sulfonyl]amino}benzoic acid methyl ester 
• 946126-93-8 C₂₃H₁₈FN₃O₇S 
• 303153-22-2 2-biphenyl-4-ylmethyl-1,1-dioxo-2,3,6,7-tetrahydro-1H-1λ⁶-[1,2]thiazepine-7-carboxylic acid isopropyl ester 
• 303153-20-0 2-(4-bromo-benzyl)-1,1-dioxo-2,3,6,7-tetrahydro-1H-1λ⁶-[1,2]thiazepine-7-carboxylic acid isopropyl ester 

Relevant articles and documents

p27 PROTEIN INDUCER

The present invention provides a p27 protein inducing agent comprising a compound represented by general formula (11) below or pharmaceutically acceptable salt thereof as an active ingredient: wherein G 1 , G 2 , G 3 and G 8 are each independently selected from -N= etc., Ring G 6 is selected from divalent aryl etc., A is selected from amino etc., G 4 is selected from oxygen etc., G 5 is selected from oxygen etc., G 7 is selected from -CH 2 - etc., and R 2 is selected from C 1-6 alkyl etc.

NOVEL COUMARIN DERIVATIVE HAVING ANTITUMOR ACTIVITY

The present invention provides a compound represented by general formula (1) below or a pharmaceutically acceptable salt thereof: wherein: X is selected from heteroaryl etc., Y1 and Y2 are selected from -N= etc., Y3 and Y4 are selected from -CH= etc., A is selected from sulfamide etc., R1 is selected from hydrogen etc., and R2 is selected from C1-6 alkyl etc. The compound or salt has sufficiently high antitumor activity, and is useful in the treatment of cell proliferative disorders, particularly cancers. The present invention also provides a pharmaceutical composition containing the compound or salt as an active ingredient.

Ring-closing metathesis to a divergent endocyclic sulfonamide template

The efficient synthesis of a novel endocyclic sulfonamide template via a ring-closing metathesis methodology is reported. A solid-supported variant of the Grubbs catalyst is shown to be effective and the suitability of the template for both combinatorial derivatization and potential incorporation into peptidomimetics is demonstrated. (C) 2000 Published by Elsevier Science Ltd.