3033-82-7

Basic information

• Product Name: 8-CHLOROQUINALDINE
• Synonyms: 8-CHLOROQUINALDINE;8-CHLORO-2-METHYLQUINOLINE;Quinaldine, 8-chloro-;Quinoline, 8-chloro-2-methyl-;2-Methyl-8-chloroquinoline;8-Chloro-2-methylquinoline 97%;8-Chloroquildine, 99%
• CAS NO: 3033-82-7
• Molecular Formula: C₁₀H₈ClN
• Molecular Weight: 177.63
• EINECS: -0
• Product Categories: Quinoline;Quinoline&Isoquinoline;Building Blocks;Halogenated Heterocycles;Heterocyclic Building Blocks;Quinolines;QuinolinesHeterocyclic Building Blocks
• Mol File: 3033-82-7.mol
• Article Data: 10

Chemical Properties

• Melting Point: 64 °C
• Boiling Point: 278.177 °C at 760 mmHg
• Flash Point: 148.736 °C
• Appearance: white to light yellow crystal powder
• Density: 1.225 g/cm³
• Vapor Pressure: 0.00732mmHg at 25°C
• Refractive Index: 1.634
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 3.17±0.50(Predicted)
• BRN: 119193
• CAS DataBase Reference: 8-CHLOROQUINALDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 8-CHLOROQUINALDINE(3033-82-7)
• EPA Substance Registry System: 8-CHLOROQUINALDINE(3033-82-7)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 36/37/38-41-37/38-22
• Safety Statements: 26-36/37/39-37/39
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 3033-82-7(Hazardous Substances Data)

Usage

Chemical Properties

white to light yellow crystal powder

InChI:InChI=1/C10H8ClN/c1-7-5-6-8-3-2-4-9(11)10(8)12-7/h2-6H,1H3

Upstream product

• 107-21-1 ethylene glycol 
• 95-51-2 o-chloroaniline 
• 75-07-0 acetaldehyde 
• 74-86-2 acetylene 
• 123-73-9 crotonaldehyde 
• 123-63-7 paracetaldehyde 
• 64-17-5 ethanol 
• 1298100-95-4 8-chloro-2-methyl-1,2,3,4-tetrahydroquinoline 
• 18826-95-4 1.3-butanediol 
• 1318193-41-7 N-(2-(8-chloroquinolin-2-yl)-1-phenylethyl)-4-methylbenzenesulfonamide 
• 123-73-9 trans-Crotonaldehyde 

Downstream Products

• 1232498-79-1 8-(methylphenylphosphanyl)quinoline 
• 1386231-75-9 potassium (2-methylquinolin-8-yl)trifluoroborate 
• 1346504-62-8 8-chloro-2-[(1E)-2-phenylethenyl]quinoline 
• 478548-99-1 2-methyl-8-(diphenylphosphino)quinoline 
• 142841-80-3 2-methyl-8-quinolineboronic acid 
• 59394-28-4 8-chloroquinoline-2-carbaldehyde 

Relevant articles and documents

Quinoline Synthesis by the Reaction of Anilines with 1,2-diols Catalyzed by Iron Compounds

The synthesis of quinoline derivatives by cyclocondensation of anilines with 1,2-ethanediol, 1,2-propanediol, and 1,2-butanediol in the presence of iron-containing catalysts was performed for the first time.

A Convenient Procedure for the Oxidative Dehydrogenation of N-Heterocycles Catalyzed by FeCl2/DMSO

A convenient catalytic procedure has been developed for the oxidative dehydrogenations of N-heterocycles. Combining catalytic FeCl2 with DMSO yields a catalyst that promotes the dehydrogenation of tetrahydroquinolines and related heterocycles under 1 bar of O2, affording the corresponding N-heteroaromatic products in moderate yields.

Synthesis of substituted quinolines by the reaction of anilines with alcohols and CCl4 in the presence of Fe-containing catalysts

Substituted quinolines were synthesized by the reaction of aniline derivatives with aliphatic alcohols and CCl4 upon the action of the FeCl3·6H2O catalyst.