3034-31-9

Basic information

• Product Name: N-phenyl isonicotinamide
• Synonyms: Isonicotinanilide;N-Phenyl isonicotinamide ,97%;N-Phenyl isonicotinicamide;N-phenylpyridine-4-carboxamide;N-Phenyl-4-pyridinecarboxamide;NSC 4266;Pyridine-4-carboxylic acid phenylamide
• CAS NO: 3034-31-9
• Molecular Formula: C₁₂H₁₀N₂O
• Molecular Weight: 198.23
• Mol File: 3034-31-9.mol
• Article Data: 33

Chemical Properties

• Melting Point: 170-172℃
• Boiling Point: 266℃
• Flash Point: 115℃
• Appearance: /
• Density: 1.227
• Storage Temp.: Inert atmosphere,Room Temperature
• CAS DataBase Reference: N-phenyl isonicotinamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-phenyl isonicotinamide(3034-31-9)
• EPA Substance Registry System: N-phenyl isonicotinamide(3034-31-9)

Safety Data

• Hazardous Substances Data: 3034-31-9(Hazardous Substances Data)

Usage

Chemical Properties

White to light yellow or grey solid

Upstream product

• 14254-57-0 4-(chlorocarbonyl)pyridine 
• 62-53-3 aniline 
• 55-22-1 pyridine-4-carboxylic acid 
• 252930-61-3 N-(2-bromophenyl)-4-pyridinecarboxamide 
• 1570-45-2 isonicotinic acid ethylester 
• 100-48-1 pyridine-4-carbonitrile 
• 98-80-6 phenylboronic acid 
• 1453-82-3 isonicotinamide 
• 14548-46-0 4-Benzoylpyridine 
• 2996-92-1 phenyl trimethylsiloxane 
• 39178-35-3 isonicotinoyl chloride hydrochloride 
• 4013-73-4 isonicotinoyl azide 

Downstream Products

• 1027219-03-9 3-Benzylsulfanyl-N-phenyl-isonicotinamide 
• 807320-43-0 1'-oxospiro[1,3'-cyclohexane(1'H)-furo[3,4-c]pyridine]-4-carboxylic acid 
• 328233-23-4 trans-1'-oxospiro[1,3'-cyclohexane(1'H)-furo[3,4-c]pyridine]-4-carboxylic acid 
• 328232-95-7 MK-0557 
• 185144-25-6 3-(2-Hydroxyethyl)-N-phenylisonicotinamide 
• 1220349-01-8 N-phenyl-3-p-tolylisonicotinamide 
• 1220349-08-5 N-phenyl-3,5-di-p-tolylisonicotinamide 
• 1389293-09-7 C₁₇H₁₅N₃O₂ 
• 1389293-06-4 C₁₉H₁₈N₂O₃ 
• 1389293-56-4 C₁₉H₂₀N₂O₃ 
• 1389293-10-0 (E)-butyl 2-(1-oxo-2-phenyl-1H-pyrrolo[3,4-c]pyridin-3(2H)-ylidene)acetate 
• 1389293-14-4 C₂₂H₁₆N₂O₃ 
• 1389293-12-2 C₁₅H₉N₃O 
• 1389293-08-6 C₁₆H₁₂N₂O₃ 

Relevant articles and documents

Practical synthesis of (1 s,4 s)-4-(methylamino)-1′ H-spiro[cyclohexane-1,3′-furo[3,4-c]pyridin]-1′-one

A practical and scalable process for the preparation of (1s,4s)-4-(methylamino)-1′H-spiro[cyclohexane-1,3′-furo[3,4-c] pyridin]-1′-one 2a, a highly functionalized and potentially useful building block for pharmaceutical research is described. The material

Designing Metallogelators Derived from NSAID-based Zn(II) Coordination Complexes for Drug-Delivery Applications

A crystal engineering approach has been invoked to design a new series of eight Zn(II) coordination complexes derived from various non-steroidal anti-inflammatory drugs (NSAIDs), namely diclofenac (DIC), ibuprofen (IBU), naproxen (NAP), flufenamic acid (FLU) and meclofenamic acid (MEC), and two co-ligands, namely N-phenyl-3-pyridylamide (3-Py) and N-phenyl-4-pyridylamide (4-Py), and Zn(NO3)2 as potential supramolecular gelators. Half of the coordination complexes thus synthesized were able to form aqueous gels (MG-3-PyMEC, MG-3-PyDIC, MG-4-PyNAP and MG-4-PyMEC). Single-crystal structures of all eight complexes revealed that they possessed a gelation-inducing 1D hydrogen-bonded network including amide…amide synthon in some cases, which supported strongly the design principles based on which these complexes were synthesized. Interestingly, one such metallogelator complex, namely 3-PyMEC, showed an intriguing anticancer property against a human breast cancer cell line (MDA-MB-231), as revealed by both MTT and cell migration assays.

Synthesis of N -Aryl Amides by Ligand-Free Copper-Catalyzed ipso -Amidation of Arylboronic Acids with Nitriles

A facile copper-catalyzed ipso-amidation of arylboronic acids with nitriles has been developed. The method provides a highly efficient and economical synthesis of N-aryl amides with a broad substrate scope.