30384-53-3

Basic information

• Product Name: methyl 2-nitrobenzenesulfonate
• Synonyms: Benzenesulfonic acid, 2-nitro-, methyl ester; Methyl 2-nitrobenzenesulfonate
• CAS NO: 30384-53-3
• Molecular Formula: C₇H₇NO₅S
• Molecular Weight: 217.1992
• Mol File: 30384-53-3.mol
• Article Data: 3

Chemical Properties

• Melting Point: 60 °C
• Boiling Point: 365°C at 760 mmHg
• Flash Point: 174.6°C
• Density: 1.453g/cm³
• Vapor Pressure: 3.39E-05mmHg at 25°C
• Refractive Index: 1.555
• Storage Temp.: Refrigerator
• Solubility: Chloroform (Slightly), Methanol (Slightly)
• CAS DataBase Reference: methyl 2-nitrobenzenesulfonate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2-nitrobenzenesulfonate(30384-53-3)
• EPA Substance Registry System: methyl 2-nitrobenzenesulfonate(30384-53-3)

Safety Data

• Hazardous Substances Data: 30384-53-3(Hazardous Substances Data)

Usage

Uses

Methyl 2-Nitrobenzenesulfonate is an intermediate used in the synthesis of Sanguinarium-13CD3 Chloride (S112502). Sanguinarium-13CD3 Chloride is the labeled analogue of Sanguinarium Chloride (S112500). Sanguinarium Chloride is a natural product with antimicrobial, anti-inflammatory, and anti-oxidant properties.

Upstream product

• 67-56-1 methanol 
• 1694-92-4 2-Nitrobenzenesulfonyl chloride 
• 124-41-4 sodium methylate 

Downstream Products

• 1059628-37-3 C₆H₄NO₅S^(1-)*C₂₈H₂₄NO₅⁽¹⁺⁾ 
• 13063-04-2 nitidine chloride 
• 50910-59-3 methyl 2-aminobenzenesulphonate 
• 4419-60-7 2-nitro-benzenesulfonic acid ; potassium-compound 
• 80-18-2 Methyl benzenesulfonate 
• 75807-76-0 1-(methylthio)-3-phenyl-2-benzothiopyrylium o-nitrobenzenesulfonate 
• 21301-48-4 4-(3-ethyl-3H-benzothiazol-2-ylidenemethyl)-7-methoxy-chromenylium; 2-nitro-benzenesulfonate 
• 21301-49-5 4-(3-ethyl-5-methoxy-3H-benzothiazol-2-ylidenemethyl)-7-methoxy-chromenylium; 2-nitro-benzenesulfonate 
• 21172-19-0 4-(3-ethyl-3H-benzothiazol-2-ylidenemethyl)-7-methyl-chromenylium; 2-nitro-benzenesulfonate 
• 21172-20-3 4-(3-ethyl-6-methyl-3H-benzothiazol-2-ylidenemethyl)-7-methyl-chromenylium; 2-nitro-benzenesulfonate 
• 111528-53-1 2-(4-dimethylamino-styryl)-1-methyl-4H-benzo[d][1,3]thiazinium; iodide 
• 113163-44-3 1,2,4-trimethyl-thiazolo[5,4-b]pyridinediium; bis-(2-nitro-benzenesulfonate ) 

Relevant articles and documents

A new synthetic approach to 7-hydroxynitidine

Benzo[c]phenanthridine alkaloid, 7-hydroxynitidine, was synthesized from readily available 2-benzyloxy-6-bromo-3,4-dimethoxybenzaldehyde 5 and napthylamine 6 using reductive amination followed by radical cyclization in eight steps. This method is highly e

Methyl-Transfer Reactions. 6. Arenesulfonates as Nucleophiles and Leaving Groups. Methyl Trinitrobenzenesulfonate

The methyl-transfer reactions from several substituted methyl arenesulfonates to potassium benzenesulfonate in sulfolane have been studied with respect to both rates and equilibria.Because the reactions were followed by proton NMR of the methoxy group, only cases of methyl arenesulfonates with quite distinct methoxy chemical shifts from the unsubstituted ester could be studied, and this, in fact, required the use of ortho substituents.Hammett plots for these data were thus impossible, but a plot of log k+ vs. log K, although somewhat scattered, did allow an estimation of the rate of the identity reaction for the unsubstituted compound.These methyl arenesulfonates, as well as methyl iodide, were placed roughly on the scale of equilibrium methylating agents studied earlier in the same solvent.Methyl 2,4,6-trinitrobenzenesulfonate is a very reactive substance not compatible with sulfolane.It is soluble and stable only in thionyl chloride among a large number of solvents attempted and methylates a few weak nucleophiles more extensively than methyl trifluoromethanesulfonate.