30405-77-7

Upstream product

• 937-31-5 (4-Nitrophenyl)acetylene 
• 7647-01-0 hydrogenchloride 
• 79887-16-4 1-ethynyl-4-(pentyloxy)benzene 
• 129660-01-1 4,6-Dichloro-2H-pyran-2-on 
• 636-98-6 p-nitrobenzene iodide 
• 75867-38-8 4-nitro-1-(trimethylsilylethynyl)benzene 
• 24393-61-1 ethyl (E)-3-(4-nitrophenyl)-2-propenoate 
• 186466-00-2 4-(N-ethyl-N-(2-hydroxyethyl)amino)-phenylacetylene 
• 861718-54-9 (Ph₃P)AuCCCCAu(PPh₃) 
• 98-88-4 benzoyl chloride 
• 115-19-5 2-methyl-but-3-yn-2-ol 
• 696-62-8 para-iodoanisole 

Downstream Products

• 1422144-12-4 5-(4-nitrobenzyl)-3-(4-nitrophenyl)-1H-pyrazole 
• 1374219-43-8 5-(4-nitrobenzyl)-3-(4-nitrophenyl)isoxazole 
• 552299-18-0 1,4-bis-(4'-azidophenyl)butadiyne 
• 30405-78-8 4,4'-(buta-1,3-diyne-1,4-diyl)dianiline 
• 110175-15-0 p-Amino-p'-nitrodiphenylbutadiyne 

Relevant academic research and scientific papers

Amino-Supported Palladium Catalyst for Chemo- and Stereoselective Domino Reactions

A solid amino-supported palladium catalyst is used in an oxidative domino reaction for the diastereoselective construction of alkyne-substituted cyclopentenol compounds. This heterogeneous catalyst exhibits high efficiency and excellent chemoselectivity, as well as good recyclability. The chemoselectivity of the domino reactions was readily controlled by switching the solvent and catalyst. Asymmetric syntheses and an oxidative carbocyclization-borylation reaction have also been developed based on the heterogeneous palladium catalyst.

Creating Dynamic Nanospaces in Solution by Cationic Cages as Multirole Catalytic Platform for Unconventional C(sp)?H Activation Beyond Enzyme Mimics

Herein we demonstrate that, based on the creation of dynamic nanospaces in solution by highly charged positive coordination cage of [Pd6(RuL3)8]28+, multirole and multi-way cage-confined catalysis is accomplisha

Method for preparing conjugated diyne compound by using copper complex

The invention relates to a method for preparing a conjugated diyne compound by using a copper complex. The method comprises the following step of: in the presence of alkali, carrying out a Glaser coupling reaction at room temperature by using alkyne as a raw material, the copper complex containing ortho-carborane Schiff base ligand as a catalyst and air as an oxidizing agent to prepare the conjugated diyne compound. Compared with the prior art, the copper complex containing the ortho-carborane Schiff base ligand is used for efficiently catalyzing the Glaser coupling reaction of alkyne to prepare the conjugated diyne compound; and the method has the advantages that selectivity is good, a catalyst dosage is low, reaction conditions are mild, a reaction can be performed in an open manner (wherein air is used as an oxidizing agent), a reaction rate is high, yield is relatively high, a substrate range is wide, and the method has wide application prospects in industry.

Ligand and additive free aerobic synthesis of diynes using Pd-CuFe2O4magnetic nanoparticles as an efficient reusable catalyst

Herein, we present the synthesis of Pd-CuFe2O4 magnetic nanoparticles as an efficient and recyclable catalyst for the oxidative homocoupling of various terminal alkynes to form symmetric 1,3-diynes. The catalyst was found to be effective with very low palladium loading. The protocol has the advantages of easy synthesis of the catalyst, mild reaction conditions, short reaction times, excellent product yields and enhanced recyclability of the catalyst.

Strategy to isolate ionic gold sites on silica surface: Increasing their efficiency as catalyst for the formation of 1,3-diynes

A new strategy is presented to obtain an efficient heterogeneous gold catalyst constituted by isolated ionic gold sites, which is known to be effective in alkyne coupling reaction. The procedure is based on a significant difference between offered gold amount and available adsorbent sites on the support, ensuring the formation of very active isolated gold ion sites. In order to achieve this purpose, mesoporous silica xerogel was grafted with an ionic silsesquioxane containing charged ammonium quaternary group. The modified silica showed 0.25 mmol of cationic sites per gram of material and presented thermal stability up to 200 °C. This material was applied as support for immobilization of Au(III) ions as square planar AuCl4? complex. The gold amount offered was just 12 % of the exchangeable capacity. The catalyst was efficiently applied in the cross coupling reactions, in which only 0.22 mol% was applied to obtain symmetric and non-symmetric 1,3-diynes.

Chemoselective Cobalt(I)-Catalyzed Cyclotrimerization of (Un)Symmetrical 1,3-Butadiynes for the Synthesis of 1,2,4-Regioisomers

The cobalt(I)-catalyzed cyclotrimerization of (un)symmetrical 1,4-disubstituted 1,3-butadiynes is presented. In the case of unsymmetrical 1,3-butadiynes, this reaction can generate eight 1,2,4-substituted and four 1,3,5-substituted isomers. A single 1,2,4-substituted isomer was formed in excellent yields (up to 99%) and exclusive regioselectivities (>99:1) when symmetrical or a 1,3-butadiyne with an aryl or alkyl substituent and a trimethylsilyl group were applied. A large number of products accepting a wide variety of functional groups were synthesized.

Synergistic effect of bimetallic PdAu nanocrystals on oxidative alkyne homocoupling

Bimetallic PdAu nanocrystals with different component ratios were obtained to investigate alkyne homocoupling. We found that the synergistic effect of Pd and Au plays an important role in the reaction. Alkynes with a variety of substituent groups could ef

A Sustainable, User-Friendly Protocol for the Pd-Free Sonogashira Coupling Reaction

We herein present a new catalytic system for the palladium-free Sonogashira coupling reaction. The catalytically active moiety is formed in situ, in a straightforward and user-friendly manner, by combining a widely available low-cost copper salt and an N-

NNN-pincer-copper complex immobilized on magnetic nanoparticles as a powerful hybrid catalyst for aerobic oxidative coupling and cycloaddition reactions in water

A simple and reliable methodology is described for preparing the first heterogeneous NNN-pincer-copper hybrid catalyst with a high control over surface composition. The strategy relies on the covalently bonding of 2-aminopyridine to cyanuric chloride-functionalized magnetic nanoparticles followed by complexation with CuI. These claims are confirmed by different characterization methods such as SEM, TEM, FT-IR, TGA, ICP, XRD, and elemental analysis. The finely engineered supported catalyst is employed in the aerobic oxidative coupling of terminal alkynes and click reaction using only 0.38 and 0.04 mol% catalyst, respectively. All reactions perform under solvent-free condition or green solvent H2O. Also, the catalyst is readily recovered and reused for up to 8 and 6 subsequent runs in click and homocoupling reactions without significant loss of activity or leaching.

A new access to tri(1-naphthyl)phosphine and its catalytically active palladacycles and luminescent Cu(I) complex

New approach to synthesis of tri(1-naphthyl)phosphine (Np3P) and its application for design of new Pd(II) and Cu(I) complexes are reported. This phosphine has been prepared in 32% yield through exhaustive P–H arylation of РН3 with 1-chloronaphthalene in the superbasic t-BuOK/DMSO system at 70 °C. The Np3P was found to readily reacts with chloro-bridged dimers, [(κ2-C,N)Pd(μ-Cl)]2 (κ2-C,N = PhCH2NMe2 (2a) or FcCH2NMe2 (2b), to give new mononuclear palladacycles [(κ2-C,N)Pd(Np3P)Cl] (3, 4), in which metal has a square-planar geometry. These complexes show good catalytic activity in the Sonogashira reaction under low catalyst loadings (2 mol% Pd) and relatively mild conditions. We also synthesized and characterized first Cu(I) complex with Np3P, namely, [Cu(phen)(Np3P)I], that exhibits red emission (λmax = 650 nm) at room temperature.