304460-41-1Relevant academic research and scientific papers
Pd(ii)-Catalyzed aerobic 1,2-difunctionalization of conjugated dienes: Efficient synthesis of morpholines and 2-morpholones
Wen, Ke,Wu, Zhengxing,Chen, Buyun,Chen, Jianzhong,Zhang, Wanbin
, p. 5618 - 5625 (2018)
A novel and efficient methodology concerning the Pd(ii)-catalyzed intermolecular difunctionalization of conjugated dienes is reported to synthesize a series of functionalized morpholines and 2-morpholones. Widely distributed and easily obtained β-amino alcohols and α-amino acids, as starting nitrogen and oxygen sources, are successfully applied in the difunctionalization of conjugated dienes respectively. The majority of the desired products were obtained in moderate to excellent yields. Oxygen was successfully employed as a terminal oxidant. Further transformation of the generated products allowed for the expansion of structural diversity.
Palladium-catalyzed intramolecular reductive olefin hydrocarbonation: Benzylic hydrogen serving as a new hydrogen donor
Dong, Xu,Cui, Jie,Song, Jian,Han, Ying,Liu, Qing,Dong, Yunhui,Liu, Hui
supporting information, p. 4903 - 4906 (2017/07/11)
A palladium-catalyzed intramolecular hydrocarbonation of unactivated alkenes was achieved, in which toluene is used as a hydrogen donor for the first time. The radical transfer hydrogenation is designed and realized based on the Bond Dissociation Energy (
Facile preparation of α-amino ketones from oxidative ring-opening of aziridines by pyridine N-oxide
Luo, Zhi-Bin,Wu, Jing-Yu,Hou, Xue-Long,Dai, Li-Xin
, p. 3428 - 3430 (2008/09/19)
The oxidative ring-opening reaction of a variety of activated aziridines by pyridine N-oxide provided α-amino ketones or α-amino aldehydes in good yields. The Royal Society of Chemistry.
A convenient and highly productive aminohydroxylation protocol employing an osmium-diamine catalyst
Muniz, Kilian,Almodovar, Iriux,Streuff, Jan,Nieger, Martin
, p. 1831 - 1835 (2007/10/03)
In situ generated osmium-diamine chelates from 2,3-diaminopropionic acid or diaminosuccinic acid represent efficient catalysts for the highly productive aminohydroxylation of alkenes. The reaction can be employed with various osmium salts and successful c
