304873-79-8

Upstream product

• 53292-90-3 cis-4-tert-butoxycarbonylaminocyclohexane-1-ylcarboxylic acid 
• 6638-79-5 N,O-dimethylhydroxylamine*hydrochloride 

Downstream Products

• 1246609-97-1 tert-butyl (1s,4s)-4-propioloylcyclohexylcarbamate 
• 1246609-60-8 6-((1s,4s)-4-(3-((6-aminopyridin-3-yl)methyl)ureido)cyclohexyl)-2-(phenylamino)-N-(2-(piperidin-1-yl)ethyl)nicotinamide 
• 1246609-98-2 ethyl 6-((1s,4s)-4-(tert-butoxycarbonylamino)cyclohexyl)-2-(phenylamino)nicotinate 
• 1246609-99-3 6-((1s,4s)-4-(tert-butoxycarbonylamino)cyclohexyl)-2-(phenylamino)nicotinic acid 
• 1246610-00-3 tert-butyl (1s,4s)-4-(6-(phenylamino)-5-(2-(piperidin-1-yl)ethylcarbamoyl)pyridin-2-yl)cyclohexylcarbamate 
• 1246610-01-4 6-((1s,4s)-4-aminocyclohexyl)-2-(phenylamino)-N-(2-(piperidin-1-yl)ethyl)nicotinamide 
• 1246610-02-5 bis-tert-butyl (1s,4s)-4-(6-(phenylamino)-5-(2-(piperidin-1-yl)ethylcarbamoyl)pyridin-2-yl)cyclohexylcarbamate 

Relevant academic research and scientific papers

PYRAZOLYL COMPOUNDS AND METHODS OF USE THEREOF

Compounds having activity as chemotherapeutic agents are provided. The compounds have the following structure (I): or a pharmaceutically acceptable salt, stereoisomer, isotopic form or prodrug thereof, wherein R1a, R1b, R1c, R1d, L, and are as defined herein. Methods associated with preparation and use of such compounds, pharmaceutical compositions comprising such compounds and methods for treating cancer (e.g., hematological cancers) are also provided.

ANTICANCER DERIVIATIVES, PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF

The invention relates to nicotinamide derivatives which can be used as anticancer drugs.