30490-54-1

Basic information

• Product Name: 2-chloro-9-acridinecarbonitrile
• Synonyms: 2-chloro-9-acridinecarbonitrile
• CAS NO: 30490-54-1
• Molecular Formula: C₁₄H₇ClN₂
• Molecular Weight: 238.67178
• Mol File: 30490-54-1.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-chloro-9-acridinecarbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-chloro-9-acridinecarbonitrile(30490-54-1)
• EPA Substance Registry System: 2-chloro-9-acridinecarbonitrile(30490-54-1)

Safety Data

• Hazardous Substances Data: 30490-54-1(Hazardous Substances Data)

Upstream product

• 326-62-5 2-fluorophenyl acetonitrile 
• 100-00-5 4-chlorobenzonitrile 
• 7035-03-2 2-methoxy-benzeneacetonitrile 
• 140-29-4 phenylacetonitrile 

Relevant articles and documents

A simple way to some sophisticated fused nitrogen heterocycles

Selected nitroarenes were found to react with arylmethylene compounds prone to form benzylic-type carbanion to give fused nitrogen heterocycles in the presence of silylating agent.

REACTION OF 4-CHLORO-1-NITROBENZENE WITH o-SUBSTITUTED PHENYLACETONITRILES; SYNTHESIS OF 8-CHLORO-1-METHYL(AND METHYLTHIOMETHYL)-6-(2-SUBSTITUTED PHENYL)-4H-s-TRIAZOLO-1,4-BENZODIAZEPINES

Reactions of 4-chloro-1-nitrobenzene with 2-methyl-, 2-methoxy- and 2-(methylthio)phenylacetonitrile in methanolic potassium hydroxide gave mixture from which the excepted 3-aryl-5-chloro-2,1-benzisoxazoles Ia-c were isolated in addition to the 2H-indoles IIIa and IIIc and acridines VIII and IX.The 2,1-benzisoxazoles were reduced to the 2-aminobenzophenones XIIa-c which were transformed via the phthalimidoacetamido compounds XIIIa-c to 5-aryl-7-chloro-1,3-dihydro-1,4-benzodiazepine-2-ones XVa-c.Treatment with phosphorus pentasulfide led to the thiones XVIa-c which reacted in boiling butanol either with acetohydrazide or with (methylthio)acetohydrazide to give the title compounds XVIIa-c and XVIIIa-c.They showed only weak anticonvulsant, incoordinating and central depressant effects.