305381-67-3

Usage

Uses

Used in Chemical Industry:
1-METHYL-1H-1,2,3-BENZOTRIAZOLE-5-CARBOXYLIC ACID is used as a corrosion inhibitor for protecting metals from corrosion in metalworking fluids, cooling water systems, and oil and gas production. Its effectiveness in preventing metal corrosion makes it a valuable component in these applications.
Used in Pharmaceutical Industry:
1-METHYL-1H-1,2,3-BENZOTRIAZOLE-5-CARBOXYLIC ACID is studied for its potential antifungal and antimicrobial activities, making it a promising candidate for the development of new pharmaceuticals targeting various infections and diseases.
Used in Agricultural Industry:
1-METHYL-1H-1,2,3-BENZOTRIAZOLE-5-CARBOXYLIC ACID is of interest for the development of new agrochemicals due to its potential antifungal and antimicrobial properties, which can be utilized to protect crops from various pathogens and pests, thereby enhancing crop yield and quality.

InChI:InChI=1/C8H7N3O2/c1-11-7-3-2-5(8(12)13)4-6(7)9-10-11/h2-4H,1H3,(H,12,13)

Upstream product

• 453-71-4 3-nitro-4-fluorobenzoic acid 
• 41263-74-5 4-(methylamino)-3-nitrobenzoic acid 
• 66315-16-0 methyl 3-amino-4-(methylamino)benzoate 
• 36242-50-9 4-methylamino-3-nitro-benzoic acid methyl ester 
• 66315-15-9 3-amino-4-(methylamino)benzoic acid 

Downstream Products

• 305381-87-7 cyclohexen-3-on-1-yl 1-methylbenzotriazole-5-carboxylate 
• 499785-52-3 ethyl 1-methyl-1H-benzo[d][1,2,3]triazole-5-carboxylate 
• 423768-38-1 1-methyl-1H-1,2,3-benzotriazole-5-carbonyl chloride 

Relevant academic research and scientific papers

The discovery of new scaffold of plant activators: From salicylic acid to benzotriazole

Started from salicylic acid (SA) and related commercialized plant activators, based on molecular three-dimensional shape and pharmacophore similarity comparison (SHAFTS), a new lead compound benzotriazole was predicted and a series of benzotriazole derivatives were designed and synthesized. The bioassay showed that benzotriazole had high activity against a broad spectrum of diseases including fungi and oomycetes in vivo, but no activity in vitro. And the introduction of proper groups at the 1’-position and 5’-position was beneficial to the activity. So, they had the potential to be exploited as novel plant activators.

HETEROCYCLIC COMPOUNDS FOR THE INHIBITION OF PASK

Disclosed herein are new heterocyclic compounds and compositions and their application as pharmaceuticals for the treatment of disease. Methods of inhibiting PAS Kinase (PASK) activity in a human or animal subject are also provided for the treatment of diseases such as diabetes mellitus.

INHIBITORS OF HISTONE DEACETYLASE

The invention relates to the inhibition of histone deacetylase. The invention provides compounds and methods for inhibiting histone deacetylase enzymatic activity. The invention also provides compositions and methods for treating cell proliferative diseases and conditions.