3055-87-6

Basic information

• Product Name: 3-PHENYLTHIOPROPIONITRILE
• Synonyms: 3-PHENYLTHIOPROPIONITRILE;2-Cyanoethyl phenyl sulfide;3-(Phenylthio)propanenitrile;3-(Phenylthio)propanonitrile;NSC 2238
• CAS NO: 3055-87-6
• Molecular Formula: C₉H₉NS
• Molecular Weight: 163.24
• Mol File: 3055-87-6.mol
• Article Data: 47

Chemical Properties

• Boiling Point: 306℃
• Flash Point: 139℃
• Appearance: /
• Density: 1.10
• Vapor Pressure: 0.000814mmHg at 25°C
• Refractive Index: 1.573
• CAS DataBase Reference: 3-PHENYLTHIOPROPIONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-PHENYLTHIOPROPIONITRILE(3055-87-6)
• EPA Substance Registry System: 3-PHENYLTHIOPROPIONITRILE(3055-87-6)

Safety Data

• Hazardous Substances Data: 3055-87-6(Hazardous Substances Data)

Usage

General Description

3-Phenylthioproprionitrile is a compound with the chemical formula C9H7NS. It is a colorless to light yellow liquid that is used in the manufacturing of pharmaceuticals and in organic synthesis. 3-Phenylthioproprionitrile is known for its strong foul odor and is considered to be toxic if ingested, inhaled or comes in contact with skin. It is also a known irritant to eyes and skin. The compound is not readily biodegradable and may persist in the environment for extended periods. It is essential to handle 3-Phenylthioproprionitrile with caution and in accordance with proper safety protocols.

InChI:InChI=1/C9H9NS/c10-7-4-8-11-9-5-2-1-3-6-9/h1-3,5-6H,4,8H2

Upstream product

• 74338-75-3 2-cyanoethyl(phenyl)sulfoxide 
• 108-86-1 bromobenzene 
• 107-13-1 acrylonitrile 
• 7677-24-9 trimethylsilyl cyanide 
• 103-04-8 (phenylthio)acetic acid 
• 882-33-7 diphenyldisulfane 
• 108-98-5 thiophenol 
• 591-50-4 iodobenzene 
• 2417-90-5 bromopropionitrile 

Downstream Products

• 10154-75-3 3-benzenesulfonyl-propionitrile 
• 1424-49-3 chloro-2 thiophenyl-3 propionitrile 
• 74338-75-3 2-cyanoethyl(phenyl)sulfoxide 
• 882-33-7 diphenyldisulfane 
• 10154-74-2 3-(phenylsulfonyl)propanamide 
• 10154-71-9 3-(phenylsulfonyl)propionic acid 
• 131981-89-0 3-Benzenesulfinyl-3-fluoro-propionitrile 
• 79496-92-7 (E)-1,1-diethoxy-3-phenylsulphinylnon-2-ene 
• 79496-85-8 (E)-1-methoxycarbonyl-2-phenylsulphinylhex-1-ene 

Relevant articles and documents

One-pot odorless thia-Michael reaction by copper ferrite nanoparticle-catalyzed reaction of elemental sulfur, aryl halides and electron-deficient alkenes

In this article we report a non-odorous protocol for the high yield formation of aryl-alkyl sulfides by the reaction of aryl iodides, bromides and boronic acids with elemental sulfur and electron-deficient alkenes, catalyzed by copper ferrite nanoparticles. The catalyst was easily separated using an external magnetic bar and recycled for subsequent runs, its catalytic activity being preserved.

Extended Pummerer fragmentation mediated by carbon dioxide and cyanide

Pummerer rearrangement reactions generate sulfur (II) oxidation state from sulfur (IV) starting materials in the presence of activating reagents. We found unprecedented transformation of vinyl sulfoxide; disulfide formation reactions mediated by atmospheric pressure of carbon dioxide in extended Pummerer rearrangement reactions. Only under CO2 atmosphere, we observed moderate to high yields of disulfide starting from sulfur (IV) starting materials. Investigations on the reaction mechanism revealed that the degradation of the starting materials and the products was significant in the absence of CO2. Further evidence for the suggested reaction mechanism was obtained by a cross-over experiment and a radical trapping reagent.

Pyrimidine-derived disulfides as potential antimicrobial agents: Synthesis and evaluation in vitro

Antibiotic resistance is a worldwide problem. The synthesis and evaluation of new antimicrobial compounds, without cytotoxicity against human cells, are highly desired. In this paper, the preparation of a class of pyrimidine-derived disulfides is describe