74338-75-3

Basic information

• Product Name: 3-PHENYLSULFINYLPROPIONITRILE
• Synonyms: 3-PHENYLSULFINYLPROPIONITRILE
• CAS NO: 74338-75-3
• Molecular Formula: C₉H₉NOS
• Molecular Weight: 0
• Mol File: 74338-75-3.mol
• Article Data: 21

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-PHENYLSULFINYLPROPIONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-PHENYLSULFINYLPROPIONITRILE(74338-75-3)
• EPA Substance Registry System: 3-PHENYLSULFINYLPROPIONITRILE(74338-75-3)

Safety Data

• Hazardous Substances Data: 74338-75-3(Hazardous Substances Data)

Upstream product

• 3055-87-6 3-(phenylthio)propionitrile 
• 108-98-5 thiophenol 
• 107-13-1 acrylonitrile 

Downstream Products

• 74338-81-1 2-phenylsulphinyloct-1-ene 
• 74338-90-2 1-hydroxy-1-(1-phenylsulphinylethenyl)cyclohexane 
• 133846-09-0 4,4-di(ethoxycarbonyl)-2-phenylsulphinylbut-1-ene 
• 133846-14-7 2-phenylsulphinyldec-1-ene 
• 79496-84-7 (E)-1-bromo-2-phenylsulphinylhex-1-yne 
• 79496-82-5 3,3-diethoxy-2-phenylsulphinylprop-1-ene 
• 79496-92-7 (E)-1,1-diethoxy-3-phenylsulphinylnon-2-ene 
• 95303-88-1 9-hydroxy-2-phenylsulphinylnon-1-ene 
• 139370-98-2 3-(p-tolyloxy)-2-phenylsulfinyl-1-propene 
• 139370-97-1 3-(4-chlorophenoxy)-2-phenylsulfinyl-1-propene 
• 3055-87-6 3-(phenylthio)propionitrile 
• 131981-85-6 3-Fluoro-3-phenylsulfanyl-propionitrile 
• 10154-75-3 3-benzenesulfonyl-propionitrile 
• 107-13-1 acrylonitrile 

Relevant articles and documents

Extended Pummerer fragmentation mediated by carbon dioxide and cyanide

Pummerer rearrangement reactions generate sulfur (II) oxidation state from sulfur (IV) starting materials in the presence of activating reagents. We found unprecedented transformation of vinyl sulfoxide; disulfide formation reactions mediated by atmospheric pressure of carbon dioxide in extended Pummerer rearrangement reactions. Only under CO2 atmosphere, we observed moderate to high yields of disulfide starting from sulfur (IV) starting materials. Investigations on the reaction mechanism revealed that the degradation of the starting materials and the products was significant in the absence of CO2. Further evidence for the suggested reaction mechanism was obtained by a cross-over experiment and a radical trapping reagent.

Acid-Catalyzed Oxidative Addition of Thiols to Olefins and Alkynes for a One-Pot Entry to Sulfoxides

An oxidative variant of the thiol-ene reaction has been developed, achieving the direct addition of thiols to olefins to form sulfoxides. The reaction uses tert-butyl hydroperoxide as oxidant and methanesulfonic acid as catalyst. The latter is believed to catalyze the oxidation of the intermediate sulfide to the sulfoxide. No special precautions are necessary to exclude oxygen, yet the products are formed without oxidation at the β-position. Styrenes, acrylic acid derivatives, alkynes, and thiophenols gave the highest yields, while aliphatic olefins and thiols were less effective.

Pyrimidine-derived disulfides as potential antimicrobial agents: Synthesis and evaluation in vitro

Antibiotic resistance is a worldwide problem. The synthesis and evaluation of new antimicrobial compounds, without cytotoxicity against human cells, are highly desired. In this paper, the preparation of a class of pyrimidine-derived disulfides is describe