849428-89-3Relevant academic research and scientific papers
A short synthesis of (-)-deoxoprosophylline
Jourdant, Angelique,Zhu, Jieping
, p. 249 - 259 (2007/10/03)
Syntheses of (-)-deoxoprosophylline from chiral L-N,N-dibenzylserine (TBDMS) aldehyde is reported. A highly diastereoselective nucleophilic addition of Buechi's Grignard reagent to chiral serinal followed by an intramolecular reductive amination of ω-oxo
Asymmetric total synthesis of (-)-deoxoprosophylline
Jourdant, Angélique,Zhu, Jieping
, p. 3431 - 3434 (2007/10/03)
Asymmetric syntheses of (-)-deoxoprosophylline from chiral L-N,N-dibenzyl serine (TBDMS) aldehyde is reported. A highly diastereoselective intramolecular reductive amination of ω-oxo amino diol is a key step of the present synthesis.
