306-12-7 Usage
Brand name
Mapharsen (Parke-Davis).
Industrial uses
Palladium dissolves in hot oxidising acids. Palladium is used as a hydrogenation catalyst, for H2/D2/T2separation and purification as well as a catalyst
in the Wacker process. The Wacker process, which facilitates the oxidation of ethylene to acetaldehyde, was
the first organopalladium reaction that was applied on an industrial scale.
Safety Profile
Poison by ingestion and intravenous routes. When heated to decomposition it emits toxic fumes of NOx and As
Enzyme inhibitor
This sulfhydryl-reactive arsenical (FW = 199.04 g/mol; CAS 306-12-7), variously named Mapharsen, Ehrlich-5, oxyphenarsine, oxarsan, arsinoxide, 3-amino-4-hydroxybenzenearsenoxide, and 2-amino-4-arsenosophenol, was originally developed by Nobelist Paul Ehrlich as an anti-syphilis drug. (Note: do not confuse this compound with oxophenylarsine, also known phenylarsine oxide). It is now used as an antiprotozomal agent, particularly against Trypanosoma. Oxophenarsine is typically supplied as the hydrochloride (FW = 235.50 g/mol) and is readily soluble in water. (See also Dichlorophenarsine) Target(s): acetyl-CoA acyltransferase; actomyosin ATPase; aldehyde dehydrogenase; alkaline phosphatase; asparagine synthetase; ATPase, rat brain; ATPase, trypanosomal; cathepsin; cholinesterase; deoxyribonuclease; diisopropylfluorophosphatase; γ-glutamyl hydrolase, or pteroylglutamate conjugase; glyceraldehyde-3-phosphate dehydrogenase; a-glycerophosphate oxidase; hexokinase; myosin ATPase; pyrophosphatase; pyruvate decarboxylase; pyruvate oxidase; ribose-5-phosphate isomerase; succinate dehydrogenase; succinate oxidase; urease.
Check Digit Verification of cas no
The CAS Registry Mumber 306-12-7 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 3,0 and 6 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 306-12:
(5*3)+(4*0)+(3*6)+(2*1)+(1*2)=37
37 % 10 = 7
So 306-12-7 is a valid CAS Registry Number.
InChI:InChI=1/C6H6AsNO2/c8-5-3-4(7-10)1-2-6(5)9/h1-3,9H,8H2
