30616-74-1

Basic information

• Product Name: Thiophene, 2-(1-phenylethenyl)-
• CAS NO: 30616-74-1
• Molecular Formula: C12H10S
• Molecular Weight: 186.277
• Mol File: 30616-74-1.mol
• Article Data: 28

Chemical Properties

• CAS DataBase Reference: Thiophene, 2-(1-phenylethenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Thiophene, 2-(1-phenylethenyl)-(30616-74-1)
• EPA Substance Registry System: Thiophene, 2-(1-phenylethenyl)-(30616-74-1)

Safety Data

• Hazardous Substances Data: 30616-74-1(Hazardous Substances Data)

Upstream product

• 91962-59-3 1-phenyl-1-(thiophen-2-yl)ethan-1-ol 
• 3437-95-4 2-Iodothiophene 
• 98-81-7 1-bromovinylbenzene 
• 88-15-3 2-Acetylthiophene 
• 100-58-3 phenylmagnesium bromide 
• 100-42-5 styrene 
• 1779-49-3 Methyltriphenylphosphonium bromide 
• 135-00-2 2-Benzoylthiophene 
• 3262-89-3 triphenylboroxine 
• 98-86-2 acetophenone 
• 188290-36-0 thiophene 
• 536-74-3 phenylacetylene 
• 108-86-1 bromobenzene 
• 96-43-5 2-thienyl chloride 

Downstream Products

• 1343477-47-3 2,2,2-trifluoro-1-[5-phenyl-5-(thiophen-2-yl)-4,5-dihydro-2,2'-bifuran-3-yl]ethanone 
• 1343477-45-1 2,2,2-trifluoro-1-[5-phenyl-2,5-di(thiophen-2-yl)-4,5-dihydrofuran-3-yl]ethanone 
• 1343477-50-8 2,2,2-trifluoro-1-[2-methyl-5-phenyl-5-(thiophen-2-yl)-4,5-dihydrofuran-3-yl]ethanone 
• 1343477-48-4 1-[2,5-diphenyl-5-(thiophen-2-yl)-4,5-dihydrofuran-3-yl]-2,2,2-trifluoroethanone 
• 1343477-49-5 2,2,2-trifluoro-1-[2-(naphthalen-2-yl)-5-phenyl-5-(thiophen-2-yl)-4,5-dihydrofuran-3-yl]ethanone 
• 1343477-46-2 2,2,3,3,4,4,4-heptafluoro-1-[5-phenyl-2,5-di(thiophen-2-yl)-4,5-dihydrofuran-3-yl]butan-1-one 
• 1556997-27-3 3,4-dihydro-10-methyl-3,12-diphenyl-3,12-bis(2-thienyl)-10a,4a-(epoxyethano)-1,2-dioxino[3,4-b]quinolin-5(10H)-one 

Relevant articles and documents

Photoredox-Catalyzed α-Aminomethyl Carboxylation of Styrenes with Sodium Glycinates: Synthesis of γ-Amino Acids and γ-Lactams

A visible-light photoredox-catalyzed reductive α-aminomethyl carboxylation of styrenes with sodium glycinates and CO2 has been developed to synthesize a series of α,α-disubstituted γ-amino acids and γ-lactams with high efficiency and regioselectivity. Notably, CO2 released from the decarboxylation step can be reused for the subsequent carboxylation. Distinct from the previous reactions with the same type of substrates leading to simple decarboxylation and olefin hydroalkylation, this process involves additional CO2 sequestration, thus leading to olefin α-aminomethyl carboxylation. These findings not only provide new access to α,α-disubstituted γ-amino acids and γ-lactams but also serve as a proof of concept for CO2 reutilization in decarboxylation reactions.

Base-promoted addition of DMA with 1,1-diarylethylenes: Application to a total synthesis of (-)-sacidumlignan B

A base-promoted addition of DMA (N,N-dimethylacetamide) to 1,1-diarylethylenes has been developed, and it provides a new strategy for the synthesis of N,N-dimethyl-4,4-diarylbutanamides from 1,1-diarylethylenes at room temperature. This method allows us to achieve the goal of synthesizing (-)-sacidumlignan B, and provides simple operation and broad substrate scope by avoiding the use of transition metal catalysts.

Regiodivergent DH or HD Addition to Alkenes: Deuterohydrogenation versus Hydrodeuterogenation

The regioselective and regiodivergent addition of H-D to a variety of 1,1-diarylalkenes was realized utilizing selectively deuterated dihydroaromatic compounds, which were generated by cobalt catalysis. The reaction was initiated by catalytic amounts of B