30718-74-2Relevant academic research and scientific papers
A molecular balance for measuring aliphatic CH-π interactions
Carroll, William R.,Zhao, Chen,Smith, Mark D.,Pellechia, Perry J.,Shimizu, Ken D.
supporting information; experimental part, p. 4320 - 4323 (2011/10/05)
A series of conformationally flexible bicyclic N-arylimides were employed as molecular balances to study the weak aliphatic CH-π interaction between alkyl and arene groups. The formation of intramolecular CH-π interactions in the folded conformers was characterized by X-ray crystallography. The strengths of the interactions were characterized in CDCl3 by the changes in the folded/unfolded ratios, as measured by 1H NMR. The CH-π interaction between a methyl group and an aromatic surface was ～1.0 kcal/mol and was easily disrupted or masked by conformational entropy and repulsive steric interactions.
NOVEL USE OF THIENOPYRIMIDINES
-
Page/Page column 37, (2010/11/27)
The present invention relates to the use of thienopyrimidine compounds for the production of pharmaceutical compositions for the treatment of inflammatory diseases.
THIENOPYRIMIDINES FOR PHARMACEUTICAL COMPOSITIONS
-
Page/Page column 53, (2010/11/25)
The present invention relates to novel pharmaceutical compositions of general formula (I) comprising thienopyrimidine compounds. Moreover, the present invention relates to the use of the thienopyrimidine compounds of the invention for the production of pharmaceutical compositions for the prophylaxis and/or treatment of diseases which can be influenced by the inhibition of the kinase activity of Mnk1 and/or Mnk2 (Mnk2a or Mnk2b) and/or variants thereof.
Synthesis and structure of four-coordinate dimethyl aluminium complexes incorporating new N,O-chelating arylamido ligands
Haquette, Pierre,Dagorne, Samuel,Welter, Richard,Jaouen, Gérard
, p. 240 - 247 (2007/10/03)
A new type of arylamido ligands with an intramolecular coordinating ortho -ether-substituent (i.e. a O,N- chelating ligand) is introduced. The achiral and chiral 4-coordinate dimethyl aluminium complexes [2-ROC6H4NR′] AlMe
Sulfonanilide compounds
-
, (2008/06/13)
Sulfonanilide compounds represented by the formula STR1 wherein R1 is a lower alkyl group or a trifluoromethyl group, R2 is a cycloalkylidenemethyl group, a group of the formula --A--R3 (wherein A is an oxygen atom, a sulf
