307308-62-9

Usage

Uses

Used in Pharmaceutical Industry:
4-(3-Fluorophenoxy)aniline is used as an intermediate in the synthesis of various pharmaceuticals for its ability to contribute to the development of new drugs with specific therapeutic properties.
Used in Dye Industry:
4-(3-FLUOROPHENOXY)ANILINE is used as a precursor in the production of dyes, where its unique molecular structure can impart distinctive color characteristics to the final products.
Used in Agrochemical Industry:
4-(3-Fluorophenoxy)aniline is utilized in the synthesis of agrochemicals, playing a role in the development of pesticides and other agricultural chemicals that are crucial for crop protection and yield enhancement.
Safety Precautions:
It is important to handle 4-(3-Fluorophenoxy)aniline with care due to its potential hazards. 4-(3-FLUOROPHENOXY)ANILINE may be harmful if swallowed, inhaled, or absorbed through the skin, and it can cause irritation to the eyes and skin. Appropriate safety measures should be taken to minimize exposure and ensure the well-being of individuals working with 4-(3-FLUOROPHENOXY)ANILINE.

Upstream product

• 34859-79-5 1-fluoro-3-(4-nitrophenoxy)benzene 
• 372-20-3 3-fluorophenol 
• 350-46-9 4-Fluoronitrobenzene 

Downstream Products

• 1244974-95-5 C₄₁H₂₆F₇N₃O₈ 
• 1457983-63-9 8-bromo-4-((4-(3-fluorophenoxy)phenyl)amino)-2-(methylthio)pyrido[4,3-d]pyrimidin-5(6H)-one 
• 1457983-62-8 4-((4-(3-fluorophenoxy)phenyl)amino)-2-(methylthio)pyrido[4,3-d]pyrimidin-5(6H)-one 
• 1457983-65-1 ethyl 4-((4-(3-fluorophenoxy)phenyl)amino)-6-methyl-2-(methylthio)pyrimidine-5-carboxylate 

Relevant academic research and scientific papers

HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF EPILEPSY

The present invention provides a novel heterocyclic compound represented by Formula [I] and a salt thereof: wherein the symbols are as defined in the specification, which is useful for treating, preventing and/or diagnosing seizure and the like in disease involving epileptic seizure or convulsive seizure (including multiple drug resistant seizure, refractory seizure, acute symptomatic seizure, febrile seizure and status epilepticus), as well as a medical use therefor.

A focused library of protein tyrosine phosphatase inhibitors

Protein tyrosine phosphatases such as PTP1B and YopH are potential targets for the development of therapeutic agents against a variety of pathological conditions including diabetes, obesity, and infection by the bacterium Yersinia pestis. A focused library of bidentate α-ketoacid-based inhibitors has been screened against several tyrosine phosphatases. Compound 2a has IC 50 values of 43 and 220 nM against YopH and PTP1B, respectively, and shows a 30-fold selectivity for PTP1B over the closely related phosphatase TCPTP.

Derivatives of quinoline as inhibitors for MEK

1. A compound of formula (I) or a pharmaceutically acceptable salt thereof. wherein: n is 0-1; X and Y are independently selected from -NH-, -O-, -S-, or -NR8- where R8 is alkyl of 1-6 carbon atoms and X may additionally comprise a CH2 group; R7 is a group (CH2)mR9 where m is 0,or an integer of from 1-3 and R9 is a substituted aryl group, an optionally substituted cycloalkyl ring of up to 10 carbon atoms, or an optionally substituted heterocyclic ring or an N-oxide of any nitrogen containing ring; R6 is a divalent cycloalkyl of 3 to 7 carbon atoms, which may be optionally further substituted with one or more alkyl of 1 to 6 carbon atom groups; or is a divalent pyridinyl, pyimidinyl, or phenyl ring; wherein the pyridinyl, pyrimidinyl, or phenyl ring may be optionally further substituted with one or more specified groups; R1, R2, R3 and R4 are each independently selected from hydrogen or various specified organic groups. Compounds are useful as pharmaceuticals for the inhibition of MEK activity.