30778-86-0

Upstream product

• 110-87-2 3,4-dihydro-2H-pyran 
• 150-19-6 O-methylresorcine 
• 3174-74-1 dihydropyran 
• 6192-52-5 p-toluenesulfonic acid monohydrate 
• 81603-62-5 2,3-dimethoxyphenyl tetrahydropyran-2-yl ether 

Downstream Products

• 340825-70-9 4-[2-(2-tetrahydropyranyloxy)-6-methoxyphenyl]-2-methylbut-2-ene 
• 120649-45-8 5-Methoxy-2-(tetrahydro-pyran-2-yl)-phenol 
• 199388-01-7 2-methoxy-6-(tetrahydro-2H-pyran-2-yloxy)benzaldehyde 
• 3147-64-6 2-hydroxy-6-methoxybenzoic acid 
• 6738-38-1 2-allyl-3-methoxyphenol 
• 135999-16-5 2-Bromo-3-methoxyphennol 
• 135678-23-8 2-Bromo-3-methoxyphenyl Toluene-p-sulphonate 
• 134594-22-2 5-Methoxynaphthalene-1-carbaldehyde 
• 35689-27-1 8-methoxynaphthalene-1-carbaldehyde 
• 144852-11-9 (+/-)-4-prenylpterocarpin 
• 144852-05-1 3-<3-methoxy-2-(3-methyl-2-butenyl)phenoxy>propionaldehyde dimethyl acetal 
• 144852-06-2 3-(2-allyl-3-methoxyphenoxy)propionaldehyde dimethyl acetal 
• 199388-05-1 4-(2-Formyl-3-methoxy-phenoxymethyl)-benzoic acid methyl ester 
• 664324-22-5 methyl 4-((2-formyl-3-hydroxyphenoxy)methyl)benzoate 

Relevant academic research and scientific papers

Zwitterionic imidazolium salt: An efficient organocatalyst for tetrahydropyranylation of alcohols

An aprotic imidazole based zwitterionic-salt, 4-(3-methylimidazolium)-butane sulfonate has been found to be an efficient organocatalyst for tetrahydropyranylation by the reaction of 3,4-dihydro-2H-pyran (DHP) and different aliphatic alcohols as well as various phenolic compounds. The notable advantages of the present method are general applicability to various alcohols, clean reaction, production of no hazardous waste, open air reaction conditions and high yields. The catalyst can be reused without the loss of significant catalytic activity.

Aminoalkylbenzofurans as serotonin (5-HT(2c)) agonists

The present invention provides serotonergic aminoalkylbenzofurans of Formula (I): where R, R1, R2, R3, R4, R4′, R5, R5′, and R12 are as described in the specification.

The use of basic resin in the preparation of tetrahydropyranyl derivatives of alcohols and phenols

A quick and efficient method for the preparation of tetrahydropyranyl (THP) derivatives of phenols and alcohols using a basic resin IRA-400 (iodide) is described.

SEROTONERGIC BENZOFURANS

The present invention provides serotonergic benzofurans of Formula (I): where A, R, R, R, R, and R are as described in the specification.

BENZOFURYLPIPERAZINES AND BENZOFURYLHOMOPIPERAZINES: SEROTONIN AGONISTS

The present invention provides serotonergic benzofurylpiperazines of Formula I: where: A is a piperazine of formula: and R, R1, R2, R3, R4, R5, R5', R6, R6', R7, R7', R8, and R8' are as described in the specification.

Regioselective synthesis of 6-substituted 2-hydroxybenzaldehyde: Efficient synthesis of the immunomodulator tucaresol and related analogues

Two new improved procedures have been developed for the preparation of the immunostimulant tucaresol 1 [4-(2-formyl-3-hydroxyphenoxymethyl)benzoic acid]. These approaches, which start from resorcinol or 2,6-dimethoxybenzaldehyde, are practical and therefore amenable to scale-up. In the case of the second approach, the multi-step synthesis reported in the literature has been reduced to three steps. Furthermore, unlike the reported method, our synthesis is versatile for the preparation of tucaresol analogues. The method is general and applicable for the preparation of 6-substituted 2-hydroxybenzaldehydes.

Regioselectivity in the Reductive Cleavage of Pyrogallol Derivatives: Reductive Electrophilic Substitution of Acetals of 2,3-Dimethoxyphenol

Acetals of 2,3-dimethoxyphenol were used as the starting materials for the transformation of 1,2,3-trioxygenated benzenes into various 1-oxygenated-2,3-dicarbon-substituted benzenes, via regioselective reductive electrophilic substitution of the 2-methoxy

Regioselectivity in the Reactions of Methoxydehydrobenzenes with Furans. Part 1. Reactions of 3-Methoxydehydrobenzene and 3-(Methoxycarbonyl)dehydrobenzene with 2-Substituted Furans.

The isomer ratios for the cycloadducts obtained for the reaction of 3-methoxydehydrobenzene, generated from 2-amino-6-methoxybenzoic acid by aprotic diazotization, or from 2-bromo-3-methoxyphenyl toluene-p-sulphonate by treatment with butyllithium, and fo

Boron Trifluoride-Catalyzed Rearrangement of 2-Aryloxytetrahydropyrans: A New Entry to C-Arylglycosidation

Treatment of 2-aryloxytetrahydropyrans with boron trifluoride afforded 2-aryltetrahydropyrans via rearrangement in good yield.Aryl O-glycopyranosides were converted into the corresponding C-glycopyranosides by the same procedure.