307989-41-9

Upstream product

• 102878-31-9 acetic acid-(3-mercapto-4-methyl-anilide) 
• 13632-07-0 N-(4-methyl 3-methylsulfonylbenzene)acetamide 
• 90222-83-6 1-methyl-2-(methylsulfonyl)-4-nitrobenzene 
• 861611-32-7 acetic acid-(4-methyl-3-methylsulfanyl-anilide) 
• 855941-88-7 acetic acid-(3-methanesulfonyl-4-methyl-anilide) 

Downstream Products

• 628737-01-9 2,5-dimethyl-4-(methylsulfonyl)-3-[(4-phenyl-2-thiazolyl)thio]-1H-indole-1-acetic acid 
• 628737-05-3 3-[(2-chlorophenyl)thio]-2,5-dimethyl-4-(methylsulfonyl)-1H-indole-1-acetic acid 
• 628737-04-2 3-[(3-chlorophenyl)thio]-2,5-dimethyl-4-(methylsulfonyl)-1H-indole-1-acetic acid 

Relevant academic research and scientific papers

Aniline pyrimidines, its preparation method and medical use (by machine translation)

The invention relates to: an aniline pyrimidine compound represented as the formula (I), a medicinal salt thereof, a prodrug thereof, and a hydrate or solvate thereof and also relates to: the preparation method of the compound, a medicine composition comp

GLUCAGON ANTAGONISTS/INVERSE AGONISTS

A novel class of compounds, which act to antagonize the action of the glucagon hormone on the glucagon receptor. Owing to their antagonizing effect of the glucagon receptor the compounds may be suitable for the treatment and/or prevention of any glucagon-

Glucagon antagonists/inverse agonists

Disclosed is a novel class of compounds of formula (I) wherein V, A, Y, Z, R1, E, X and D are as defined in the specification. These compounds act to antagonize the action of the glucagon hormone on the glucagon receptor. Owing to their antagonizing effect of the glucagon receptor, the compounds are suitable for treating or preventing glucagon-mediated conditions and diseases such as hyperglycemia, Type 1 diabetes, Type 2 diabetes and obesity.