90222-83-6Relevant academic research and scientific papers
Aniline pyrimidines, its preparation method and medical use (by machine translation)
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Paragraph 0127; 0231; 0232; 0233, (2018/03/01)
The invention relates to: an aniline pyrimidine compound represented as the formula (I), a medicinal salt thereof, a prodrug thereof, and a hydrate or solvate thereof and also relates to: the preparation method of the compound, a medicine composition comp
GLUCAGON ANTAGONISTS/INVERSE AGONISTS
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Page/Page column 177, (2010/02/14)
A novel class of compounds, which act to antagonize the action of the glucagon hormone on the glucagon receptor. Owing to their antagonizing effect of the glucagon receptor the compounds may be suitable for the treatment and/or prevention of any glucagon-
Glucagon antagonists/inverse agonists
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, (2008/06/13)
Disclosed is a novel class of compounds of formula (I) wherein V, A, Y, Z, R1, E, X and D are as defined in the specification. These compounds act to antagonize the action of the glucagon hormone on the glucagon receptor. Owing to their antagonizing effect of the glucagon receptor, the compounds are suitable for treating or preventing glucagon-mediated conditions and diseases such as hyperglycemia, Type 1 diabetes, Type 2 diabetes and obesity.
The Friedel-Crafts Type Methanesulfonylation of Deactivated Benzenes
Ono, Mitsunori,Nakamura, Yoshisada,Sato, Shingo,Itoh, Isamu
, p. 395 - 398 (2007/10/02)
The participation of nonionic donor-acceptor complex was suggested by the analyses of product isolated in the Friedel-Crafts reaction of m-dichlorobenzene with CH3SO2Cl in the presence of AlCl3.On the basis of these observations a new practical method of methanesulfonylation of deactivated benzenes employing methanesulfonic anhydride and CF3SO3H was developed.
