308087-90-3Relevant academic research and scientific papers
4(1H)-quinolone derivatives overcome acquired resistance to anti-microtubule agents by targeting the colchicine site of β-tubulin
Lin, Ming-Shiu,Hong, Tse-Ming,Chou, Ting-Hung,Yang, Shuenn-Chen,Chung, Wei-Chia,Weng, Chia-Wei,Tsai, Mei-Ling,Cheng, Ting-Jen Rachel,Chen, Jeremy J.W.,Lee, Te-Chang,Wong, Chi-Huey,Chein, Rong-Jie,Yang, Pan-Chyr
, (2019)
Developing new therapeutic strategies to overcome drug resistance of cancer cells is an ongoing endeavor. From among 2 million chemicals, we identi?ed ethyl 4-oxo-2-phenyl-1,4-dihydroquinoline-6-carboxylate (AS1712) as a low-toxicity inhibitor of lung can
4(1H)-QUINOLONE DERIVATIVES AND USES THEREOF
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, (2020/11/30)
Compounds of Formula (I) and methods for treating, delaying, and/or preventing the adverse effects of proliferative diseases, such as cancers including, for example, lung cancer, breast cancer, ovarian cancer, prostate cancer, head cancer, neck cancer, he
4(1H)-QUINOLONE DERIVATIVES AND USES THEREOF
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, (2020/11/09)
The invention discloses 4(1H)-quinolone derivatives and uses thereof. The derivatives are compounds represented by a formula (I). The invention provides novel compounds, compositions and methods for treating, delaying and/or preventing proliferative disea
BICYCLIC IMIDAZOL DERIVATIVES AGAINST FLAVIVIRIDAE
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Page/Page column 239-240, (2008/06/13)
Disclosed are compounds, compositions and methods for treatingFlaviviridae family virus infections.
4-quinolone derivatives having anti-inflammatory, anti-allergic, antitussive, expectorant and antithrombotic activity
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, (2008/06/13)
4-Quinolone derivatives of the present invention are useful for their anti-inflammatory, anti-allergenic, antitussive, expectorant and antithrombotic activity. Pharmaceutical compositions containing said compounds and pharmaceutically acceptable salts thereof and methods of treating humans and animals are described herein.
