308087-90-3Relevant academic research and scientific papers
4(1H)-quinolone derivatives overcome acquired resistance to anti-microtubule agents by targeting the colchicine site of β-tubulin
Lin, Ming-Shiu,Hong, Tse-Ming,Chou, Ting-Hung,Yang, Shuenn-Chen,Chung, Wei-Chia,Weng, Chia-Wei,Tsai, Mei-Ling,Cheng, Ting-Jen Rachel,Chen, Jeremy J.W.,Lee, Te-Chang,Wong, Chi-Huey,Chein, Rong-Jie,Yang, Pan-Chyr
, (2019)
Developing new therapeutic strategies to overcome drug resistance of cancer cells is an ongoing endeavor. From among 2 million chemicals, we identi?ed ethyl 4-oxo-2-phenyl-1,4-dihydroquinoline-6-carboxylate (AS1712) as a low-toxicity inhibitor of lung can
4(1H)-QUINOLONE DERIVATIVES AND USES THEREOF
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, (2020/11/09)
The invention discloses 4(1H)-quinolone derivatives and uses thereof. The derivatives are compounds represented by a formula (I). The invention provides novel compounds, compositions and methods for treating, delaying and/or preventing proliferative disea
4(1H)-QUINOLONE DERIVATIVES AND USES THEREOF
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, (2020/11/30)
Compounds of Formula (I) and methods for treating, delaying, and/or preventing the adverse effects of proliferative diseases, such as cancers including, for example, lung cancer, breast cancer, ovarian cancer, prostate cancer, head cancer, neck cancer, he
BICYCLIC IMIDAZOL DERIVATIVES AGAINST FLAVIVIRIDAE
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Page/Page column 239-240, (2008/06/13)
Disclosed are compounds, compositions and methods for treatingFlaviviridae family virus infections.
4-quinolone derivatives having anti-inflammatory, anti-allergic, antitussive, expectorant and antithrombotic activity
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, (2008/06/13)
4-Quinolone derivatives of the present invention are useful for their anti-inflammatory, anti-allergenic, antitussive, expectorant and antithrombotic activity. Pharmaceutical compositions containing said compounds and pharmaceutically acceptable salts thereof and methods of treating humans and animals are described herein.
