30882-77-0

Upstream product

• 91-02-1 phenyl(pyridin-2-yl)methanone 
• 120153-68-6 N-benzylpiperidine-2-carbonitrile 
• 95018-47-6 {1-[(E)-tert-Butylimino-methyl]-1,4,5,6-tetrahydro-pyridin-2-yl}-phenyl-methanol 
• 615571-40-9 1,1-dimethylethyl (1S)-2-[(2S)-hydroxy(phenyl)methyl]piperidine-1-carboxylate 
• 75844-69-8 t-butyl piperidinecarboxylate 
• 85152-52-9 N-(N'-tert-butylformimidoyl)piperidine 
• 123387-56-4 erythro-N-(tert-butoxycarbonyl)-α-phenyl-2-piperidinemethanol 
• 101-82-6 2-Benzylpyridine 
• 729553-31-5 (1-Benzyl-piperidin-2-yl)-phenyl-methanone 
• 120153-69-7 2-Benzoyl-piperidine-1-carboxylic acid phenyl ester 
• 7647-01-0 hydrogenchloride 
• 7732-18-5 water 
• 5583-31-3 erythro-α-phenyl-2-piperidinemethanol 
• 42510-59-8 threo-8-oxa-7-phenyl-1-azabicyclo<4.3.0>nonan-9-one 

Downstream Products

• 5583-31-3 threo-α-phenyl-2-piperidinemethanol 
• 5583-07-3 (8aR or 8aS)-1c-phenyl-(8ar)-hexahydro-oxazolo[3,4-a]pyridin-3-ylideneamine 
• 5583-07-3 (8aR or 8aS)-1t-phenyl-(8ar)-hexahydro-oxazolo[3,4-a]pyridin-3-ylideneamine 
• 5583-31-3 (αR,2S)-phenyl 2-piperidyl methanol 
• 71413-05-3 1t,3ξ-diphenyl-(8ar)-hexahydro-oxazolo[3,4-a]pyridine 
• 615571-37-4 threo-(1-ethylpiperidin-2-yl)phenylmethanol 
• 5583-07-3 1c-phenyl-(8ar)-hexahydro-oxazolo[3,4-a]pyridin-3-ylideneamine 
• 104116-98-5 3ξ-(4-nitro-phenyl)-1c-phenyl-(8ar)-hexahydro-oxazolo[3,4-a]pyridine 

Relevant academic research and scientific papers

Concise preparation of a stable cyclic sulfamidate intermediate in the synthesis of a enantiopure chiral active diamine derivative

A classical resolution was studied and developed from 2-benzoyl-pyridine in order to prepare SSR504734, a novel antipsychotic derivative. The key step of this route is the substitution of a sulfamidate derivative by a benzamide anion with complete inversi

N-[phenyl (piperidin-2-yl) methyl]benzamide derivatives, preparation thereof, and use thereof in therapy

This invention discloses and claims a compound of general formula (I) in which R1 represents either a hydrogen atom, or an optionally substituted alkyl group, or a cycloalkylalkyl group, or an optionally substituted phenylalkyl group, or an alk

Derivative of n-[phenyl(piperidin-2-yl)methyl]benzamide, the preparation method thereof and application of same in therapeutics

Compound of general formula (I) in which A represents either a group of formula N—R1 in which R1 represents a hydrogen atom, an alkyl group, a cycloalkyl group, a phenylalkyl group, an alkenyl group or an alkynyl group, or a group of

erythro-1-naphthyl-1-(2-piperidyl)methanol: Synthesis, resolution, NMR relative configuration, and VCD absolute configuration

The erythro isomer of 1-naphthyl-1-(2-piperidyl)methanol 4, an efficient chiral modifier for asymmetric heterogeneous hydrogenation, was obtained as the major isomer (95%) in two steps while the threo isomer can be obtained as the major isomer (67%) in th

α-Lithioamine Synthetic Equivalents: Syntheses of Diastereoisomers from the Boc Piperidines

The α'-lithiations and electrophilic substitutions of selected Boc piperidines provide single or separable diastereoisomeric 2-substituted, 2,4-disubstituted, and 2,4,6-trisubstituted Boc piperidines which are readily hydrolyzed to the substituted piperidines.

A NEW AND DIASTEREOSELECTIVE SYNTHESIS OF THREO-ARYL-2-PIPERIDYLMETHANOL DERIVATIVES

A diastereoselective synthesis of threo-aryl-2-piperidyl- and aryl-1,2,3,6-tetrahydro-2-pyridylmethanol derivatives is described.The stereochemestry is controlled by intramolecularly assisted NaBH4 reduction of the intermediate carbamates 3.

α-Amino Carbanions. Preparation, Metalation, and Alkylation of Enamidines. Synthesis of Piperidine and Pyrrolidine Natural Products and Homologation of Carbonyl Compounds

Saturated heterocycles, as their tert-butylformamidines, may be transformed into enamidines, by metalation-selenation-elimination.These enamidines are valuable precursors to 2-substituted, 2,4-disubstituted, and 2,4,6-trisubstituted pyrrolidines, piperidines, and perhydroazepines, prepared in a regiospecific manner.The method is demonstrated by the synthsesis of selenopsin A and the red fire ant venom.The use of acyclic enamidines is displayed as a homologation reagent which converts carbonyl compounds to higher alkyl derivatives.