308833-37-6

Basic information

• Product Name: 2,4(1H,3H)-Pyrimidinedione, 6-[(3-ethyl-4-methylphenyl)amino]-3-(4-iodobutyl)-
• CAS NO: 308833-37-6
• Molecular Formula: C17H22IN3O2
• Molecular Weight: 427.285
• Mol File: 308833-37-6.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 2,4(1H,3H)-Pyrimidinedione, 6-[(3-ethyl-4-methylphenyl)amino]-3-(4-iodobutyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4(1H,3H)-Pyrimidinedione, 6-[(3-ethyl-4-methylphenyl)amino]-3-(4-iodobutyl)-(308833-37-6)
• EPA Substance Registry System: 2,4(1H,3H)-Pyrimidinedione, 6-[(3-ethyl-4-methylphenyl)amino]-3-(4-iodobutyl)-(308833-37-6)

Safety Data

• Hazardous Substances Data: 308833-37-6(Hazardous Substances Data)

Upstream product

• 478921-02-7 3-(4-acetoxybutyl)-6-(3-ethyl-4-methylanilino)uracil 
• 292619-97-7 3-(4-methoxybutyl)-6-(3-ethyl-4-methylanilino)uracil 
• 292619-96-6 HB-EMAU 
• 561064-19-5 1-(4-methoxybutyl)barbituric acid 
• 561064-18-4 6-chloro-3-(4-methoxybutyl)uracil 
• 98385-96-7 N-(4-Methoxybutyl)harnstoff 
• 478920-93-3 6-amino-2-methoxy-3-(4-acetoxybutyl)-4-pyrimidone 

Downstream Products

• 496943-52-3 3-{4-[4-(tert-butoxycarbonyl)piperazino-1-yl]butyl}-6-(3-ethyl-4-methylanilino)uracil 
• 1026866-47-6 1-cyclopropyl-7-(4-{4-[4-(3-ethyl-4-methyl-phenylamino)-2,6-dioxo-3,6-dihydro-2H-pyrimidin-1-yl]-butyl}-3-methyl-piperazin-1-yl)-6-fluoro-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid ethyl ester 
• 479069-86-8 1-cyclopropyl-7-(4-{4-[4-(3-ethyl-4-methyl-phenylamino)-2,6-dioxo-3,6-dihydro-2H-pyrimidin-1-yl]-butyl}-3-methyl-piperazin-1-yl)-6,8-difluoro-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid ethyl ester 
• 479069-81-3 3-{4-[1-(1-{4-fluorophenyl}-3-ethoxycarbonyl-4-oxo-6-fluoro-7-quinolyl)-4-piperazinyl]butyl}-6-(3-ethyl-4-methylanilino)uracil 
• 904688-82-0 1-cyclopropyl-7-(4-{4-[4-(3-ethyl-4-methyl-phenylamino)-2,6-dioxo-3,6-dihydro-2H-pyrimidin-1-yl]-butyl}-3-hydroxymethyl-piperazin-1-yl)-6,8-difluoro-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid ethyl ester 
• 479069-79-9 3-{4-[1-(1-{2,4-difluorophenyl}-3-ethoxycarbonyl-4-oxo-6-fluoro-7-quinolyl)-4-piperazinyl]butyl}-6-(3-ethyl-4-methylanilino)uracil 
• 496943-27-2 3-{4-[4-(3-carboxy-4-oxo-6-fluoro-7-chloroquinoline-1-yl)butylamino]butyl}-6-(3-ethyl-4-methylanilino)uracil 

Relevant articles and documents

Synthesis and antibacterial activity of 3-substituted-6-(3-ethyl-4- methylanilino)uracils

Numerous 3-substituted-6-(3-ethyl-4-methylanilino)uracils (EMAU) have been synthesized and screened for their capacity to inhibit the replication-specific bacterial DNA polymerase IIIC (pol IIIC) and the growth of Gram+ bacteria in culture. Direct alkylat

N3-substituted 6-anilinopyrimidines and methods to treat-Gram-positive bacterial and mycoplasmal infections

Compounds useful for treating Gram-positive bacterial and mycoplasmal infections are disclosed. The compounds have the general formulae shown below.

Novel heterocyclic antibacterial compounds

The invention provides heterocyclic organic compounds that inhibit bacterial DNA polymerase IIIC and type II bacterial topoisomerase. The invention further provides compounds that are useful as intermediates in the synthesis of such heterocyclic organic compounds. Syntheses and uses of such heterocyclic organic molecules are also described.