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6,7,8-Trimethoxyquinazoline-2,4(1H,3H)-dione is an organic compound that serves as a crucial intermediate in the synthesis of various pharmaceuticals. It is characterized by its quinazoline structure, which is a fused bicyclic ring system consisting of a benzene ring fused to a pyrimidine ring, and the presence of three methoxy groups attached to the 6th, 7th, and 8th positions of the quinazoline ring. 6,7,8-trimethoxyquinazoline-2,4(1H,3H)-dione plays a significant role in the development of potent antihypertensive agents.

30896-98-1

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30896-98-1 Usage

Uses

Used in Pharmaceutical Industry:
6,7,8-Trimethoxyquinazoline-2,4(1H,3H)-dione is used as an intermediate in the synthesis of Trimazosin Hydrochloride (T795515) for its application as a potent antihypertensive agent. 6,7,8-trimethoxyquinazoline-2,4(1H,3H)-dione contributes to the development of medications that help in the treatment of high blood pressure, a condition that can lead to various cardiovascular diseases if left unmanaged.
Trimazosin Hydrochloride, synthesized using 6,7,8-trimethoxyquinazoline-2,4(1H,3H)-dione, is known for its effectiveness in managing hypertension by acting on the adrenergic receptors, leading to vasodilation and a subsequent decrease in blood pressure. 6,7,8-trimethoxyquinazoline-2,4(1H,3H)-dione's role in the pharmaceutical industry is vital, as it aids in the creation of life-saving medications for patients suffering from hypertension and related cardiovascular conditions.

Check Digit Verification of cas no

The CAS Registry Mumber 30896-98-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,0,8,9 and 6 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 30896-98:
(7*3)+(6*0)+(5*8)+(4*9)+(3*6)+(2*9)+(1*8)=141
141 % 10 = 1
So 30896-98-1 is a valid CAS Registry Number.
InChI:InChI=1/C11H12N2O5/c1-16-6-4-5-7(9(18-3)8(6)17-2)12-11(15)13-10(5)14/h4H,1-3H3,(H2,12,13,14,15)

30896-98-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name 6,7,8-trimethoxy-1H-quinazoline-2,4-dione

1.2 Other means of identification

Product number -
Other names 6,7,8-Trimethoxy-2,4-chinazolindion

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:30896-98-1 SDS

30896-98-1Downstream Products

30896-98-1Relevant academic research and scientific papers

SUBSTITUTED 2-AMINO-QUINAZOLIN-4-CN COMPOUNDS FOR USE IN THE TREATMENT OF CNS DISORDERS, PAIN, STROKE, ADDICTION AND EPILEPSY, THEIR PREAPARATION AND USE AS INTERMEDIATES

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Page/Page column 39, (2008/06/13)

The present invention relates to substituted quinazoline compounds, methods for their preparation, as well as their use as intermediates for the preparation of active biomolecules .

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