30934-48-6Relevant articles and documents
Highly stereoselective synthesis of non-racemic 3-substituted dihydro-benzo[de]isoquinolinones via an addition-cyclization-substitution method
Kaczorek, Dorota,Kaw?cki, Robert
, (2020)
Substituted dihydrobenzo[de]isoquinolinones were synthesized via diastereoselective addition of Grignard reagents to the N-tert-butylsulfinylimine derived from 1,8-naphthaldehydic methyl ester, followed by cyclization and substitution at the sulfur atom. The products were obtained in 25–98% yield and with enantiomeric excess of 46–99%.