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N-alpha-Benzyloxycarbonyl-D-alanine p-nitrophenyl ester is a chemical compound that serves as a reagent in biochemical research, particularly for the synthesis and modification of peptides. It is derived from the amino acid D-alanine and features a benzyl carbonyl protective group, along with a p-nitrophenyl ester functionality that facilitates the activation of carboxyl groups in peptide synthesis. N-alpha-Benzyloxycarbonyl-D-alanine p-nitrophenyl ester is instrumental in the preparation of peptide conjugates and the investigation of enzyme activity, making it a valuable asset in peptide chemistry and bioconjugation.

30960-00-0

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30960-00-0 Usage

Uses

Used in Peptide Synthesis:
N-alpha-Benzyloxycarbonyl-D-alanine p-nitrophenyl ester is used as a reagent for the synthesis of peptides, providing a protective group that aids in the controlled formation of peptide bonds and prevents unwanted side reactions during the process.
Used in Peptide Modification:
In the field of peptide chemistry, N-alpha-Benzyloxycarbonyl-D-alanine p-nitrophenyl ester is utilized as a modifying agent to alter the properties of peptides, enhancing their stability, solubility, or biological activity.
Used in Enzyme Activity Studies:
N-alpha-Benzyloxycarbonyl-D-alanine p-nitrophenyl ester is employed as a substrate in the study of enzyme activity, particularly for enzymes that cleave peptide bonds. The p-nitrophenyl ester group allows for the monitoring of enzymatic reactions through the release of p-nitrophenol, which is colorimetrically detectable.
Used in Bioconjugation:
N-alpha-Benzyloxycarbonyl-D-alanine p-nitrophenyl ester is used as a linker in bioconjugation processes, enabling the covalent attachment of peptides to other biomolecules, such as antibodies or nanoparticles, for various applications in diagnostics, therapeutics, and research.
Used in Pharmaceutical Development:
In the pharmaceutical industry, N-alpha-Benzyloxycarbonyl-D-alanine p-nitrophenyl ester is used as a building block for the design and synthesis of peptide-based drugs, taking advantage of its reactivity and protective group to create stable and bioactive compounds.
Used in Diagnostics:
In diagnostic applications, N-alpha-Benzyloxycarbonyl-D-alanine p-nitrophenyl ester can be used as a component in the development of assays and tests that rely on the specific interactions of peptides with target molecules, such as antigens or receptors, for the detection and measurement of biological processes or diseases.

Check Digit Verification of cas no

The CAS Registry Mumber 30960-00-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,0,9,6 and 0 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 30960-00:
(7*3)+(6*0)+(5*9)+(4*6)+(3*0)+(2*0)+(1*0)=90
90 % 10 = 0
So 30960-00-0 is a valid CAS Registry Number.

30960-00-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name N-(benzyloxycarbonyl)-D-alanine p-nitrophenyl ester

1.2 Other means of identification

Product number -
Other names benzyloxycarbonyl-D-alanine p-nitrophenylester

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:30960-00-0 SDS

30960-00-0Relevant academic research and scientific papers

Analogues of the Cytostatic and Antimitogenic Agents Chlamydocin and HC-Toxin: Synthesis and Biological Activity of Chloromethyl Ketone and Diazomethyl Ketone Functionalized Cyclic Tetrapeptides

Shute, Richard E.,Dunlap, Brian,Rich, Daniel H.

, p. 71 - 78 (2007/10/02)

The synthesis and biological activity of four novel analogues of the cytostatic and antimitogenic agents chlamydocin and HC-toxin are reported in which the natural products' reactive epoxy ketone side-chain moiety is replaced by a chloromethyl or a diazom

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