309721-44-6

Basic information

• Product Name: 2-Chloro-6-fluorobromobenzene
• Synonyms: 2-Chloro-6-fluorobromobenzene;2-Bromo-1-chloro-3-fluorobenzene
• CAS NO: 309721-44-6
• Molecular Formula: C₆H₃BrClF
• Molecular Weight: 209.4434232
• Mol File: 309721-44-6.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 198℃
• Flash Point: 73℃
• Appearance: /
• Density: 1.719
• Vapor Pressure: 0.525mmHg at 25°C
• Refractive Index: 1.551
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 2-Chloro-6-fluorobromobenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Chloro-6-fluorobromobenzene(309721-44-6)
• EPA Substance Registry System: 2-Chloro-6-fluorobromobenzene(309721-44-6)

Safety Data

• Hazardous Substances Data: 309721-44-6(Hazardous Substances Data)

Usage

General Description

2-Chloro-6-fluorobromobenzene is a chemical compound with the molecular formula C6H4BrClF. It is a halogenated aromatic compound that contains chlorine, fluorine, and bromine atoms attached to a benzene ring. 2-chloro-6-fluorobromobenzene is used in organic synthesis and as an intermediate for the preparation of various pharmaceuticals and agrochemicals. Its properties and reactivity make it a valuable building block in the production of specialty chemicals and complex organic molecules. 2-Chloro-6-fluorobromobenzene is also used in research and development as a starting material for the synthesis of new compounds with potential applications in the pharmaceutical and agricultural industries.

InChI:InChI=1/C6H3BrClF/c7-6-4(8)2-1-3-5(6)9/h1-3H

Upstream product

• 625-98-9 3-chlorofluorobenzene 

Downstream Products

• 332903-74-9 N-(2-chloro-6-fluoro-phenyl)-4-methylaniline 
• 1388045-78-0 (2-bromo-3-chlorophenyl)hydrazine 
• 332903-78-3 2-chloro-N-(2-chloro-6-fluoro-phenyl)-N-p-tolylacetamide 
• 332903-83-0 1-(2-chloro-6-fluorophenyl)-5-methylindolin-2-one 
• 220991-20-8 lumiracoxib 

Relevant articles and documents

Expanding the Boundaries of Water-Tolerant Frustrated Lewis Pair Hydrogenation: Enhanced Back Strain in the Lewis Acid Enables the Reductive Amination of Carbonyls

The development of a boron/nitrogen-centered frustrated Lewis pair (FLP) with remarkably high water tolerance is presented. As systematic steric tuning of the boron-based Lewis acid (LA) component revealed, the enhanced back-strain makes water binding increasingly reversible in the presence of relatively strong base. This advance allows the limits of FLP's hydrogenation to be expanded, as demonstrated by the FLP reductive amination of carbonyls. This metal-free catalytic variant displays a notably broad chemoselectivity and generality.