310466-38-7

Basic information

• Product Name: Benzo[b]thiophene, 4-fluoro- (9CI)
• Synonyms: Benzo[b]thiophene, 4-fluoro- (9CI);4-fluorobenzo[b]thiophene;Benzo[b]thiophene, 4-fluoro-
• CAS NO: 310466-38-7
• Molecular Formula: C8H5FS
• Molecular Weight: 152.1887032
• Product Categories: HALIDE
• Mol File: 310466-38-7.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 226.229°C at 760 mmHg
• Flash Point: 90.621°C
• Appearance: /
• Density: 1.298g/cm³
• Vapor Pressure: 0.124mmHg at 25°C
• Refractive Index: 1.644
• Storage Temp.: 2-8°C(protect from light)
• CAS DataBase Reference: Benzo[b]thiophene, 4-fluoro- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Benzo[b]thiophene, 4-fluoro- (9CI)(310466-38-7)
• EPA Substance Registry System: Benzo[b]thiophene, 4-fluoro- (9CI)(310466-38-7)

Safety Data

• Hazardous Substances Data: 310466-38-7(Hazardous Substances Data)

Usage

General Description

Benzo[b]thiophene, 4-fluoro- (9CI) is a chemical compound with the molecular formula C8H5FS. It is a fluoro-substituted derivative of benzo[b]thiophene, which is a heterocyclic aromatic compound. This chemical is commonly used as a building block in organic synthesis and can also be found in some pharmaceuticals and agrochemicals. Its synthetic derivatives have been studied for their potential anti-inflammatory, anti-cancer, and antifungal properties. Additionally, it is also used in the production of dyes and pigments. However, the compound's potential hazards and health effects on humans and the environment have not been fully studied and understood. Therefore, it is important to handle this chemical with care and follow safety protocols when working with it.

InChI:InChI=1/C8H5FS/c9-7-2-1-3-8-6(7)4-5-10-8/h1-5H

Upstream product

• 220180-55-2 methyl 4-fluorobenzo[b]thiophene-2-carboxylate 
• 96-45-7 N,N'-ethylenethiourea 
• 360575-20-8 2-chloro-1-(4-fluorobenzo[b]thiophen-2-yl)ethan-1-one 
• 501944-64-5 3-fluorobenzenethioacetaldehyde diethyl acetal 
• 1263280-02-9 ethyl 4-fluorobenzo[b]thiophene-2-carboxylate 
• 437-81-0 2,6-difluorobenzaldehyde 
• 310466-37-6 4-fluoro-1-benzothiophene-2-carboxylic acid 

Downstream Products

• 34577-05-4 benzo[b]thiophen-4-yl benzoate 

Relevant articles and documents

Design and development of cyclometalated ruthenium complexes containing thiophenyl-pyridine ligand for dye-sensitized solar cells

Two new cyclometalated ruthenium sensitizers NC102 (1) and NC103 (2), where the two NCS- ligands of the N3 analog were replaced with the 2-thiophen-2-yl-pyridine and 2-benzo[b]thiophen-2-yl-pyridine ligands, respectively, were designed and synthesized for dye-sensitized solar cell applications. The effects of these two ligands on the photophysical behavior of ruthenium complexes were investigated by their optical, electrochemical, and photovoltaic properties. The sensitizer NC103 (2) with the fluoride substitution in the ligand exhibited the best cell performance with a short-circuit current (Jsc) of 9.45 mA/cm2, an open-circuit voltage (V oc) of 630 mV, and a fill factor (FF) of 0.71, giving an overall power conversion efficiency of (η) 4.22% under simulated AM 1.5 irradiation.

An improved synthesis of substituted benzo[b]thiophenes using microwave irradiation

An easy and high-yielding method for the synthesis of substituted benzo[b]thiophenes using microwave irradiation is described.

Dihydroimidazo[2,1-b]thiazole and dihydro-5h-thiazolo[3,2-A]pyrimidines as antidepressant agents

The present invention relates to certain novel substituted dihydroimidazo[2,1-b]thiazole and dihydro-5H-thiazolo[3,2-a]pyrimidine compounds of Formula (I) including pharmaceutically acceptable salts thereof in which have affinity for 5-HT1A receptors and which inhibits neuronal reuptake of 5-hydroxytryptamine and/or noradrenaline, to processes for their preparation, to pharmaceutical compositions containing them and to their use in the treatment of depression, anxiety, psychoses (for example schizophrenia), tardive dyskinesia, obesity, drug addiction, drug abuse, cognitive disorders, Alzheimer's disease, obsessive-compulsive behaviour, panic attacks, social phobias, eating disorders such as bulimia, anorexia, snacking and binge eating, non-insulin dependent diabetes mellitus, hyperglycaemia, hyperlipidaemia, stress, as an aid to smoking cessation and in the treatment and/or prophylaxis of seizures, neurological disorders such as epilepsy and/or in which there is neurological damage such as stroke, brain trauma, cerebral ischaemia, head injuries and haemorrhage.