31084-61-4Relevant academic research and scientific papers
Catalytic Selective Oxidative Coupling of Secondary N-Alkylanilines: An Approach to Azoxyarene
Ke, Lei,Zhu, Guirong,Qian, Hui,Xiang, Guangya,Chen, Qin,Chen, Zhilong
, p. 4008 - 4013 (2019)
Azoxyarenes are among important scaffolds in organic molecules. Direct oxidative coupling of primary anilines provides a concise fashion to construct them. However, whether these scaffolds can be prepared from secondary N-alkylanilines is not well explored. Here, we present a catalytic selective oxidative coupling of secondary N-alkylaniline to afford azoxyarene with tungsten catalyst under mild conditions. In addition, azoxy can be viewed as a bioisostere of alkene and amide. Several "azoxyarene analogues" of the corresponding bioactive alkenes and amides showed comparable promising anticancer activities.
EFFECT OF SUBSTITUENTS IN THE RING ON THE HYDROGENATION OF AROMATIC NITRO COMPOUNDS IN THE PRESENCE OF METAL COMPLEX CATALYSIS
Klyuev, M. V.
, p. 525 - 529 (2007/10/02)
In the presence of the complex of palladium with poly(4-vinylpyridine), grafted to the surface of polyethylene, the rates of hydrogenation of aromatic nitro compounds and of hydrogenation amination of 2-methylpropanal by aromatic nitro compounds depend on the nature of the substituent and decrease with increase in absolute value of the Hammett constant.
