31085-57-1

Upstream product

• 76-83-5 trityl chloride 
• 58-61-7 adenosine 

Downstream Products

• 137965-05-0 2'-O-Triflyl-3',5'-di-O-trityl-N⁶-trityladenosine 
• 137964-99-9 2-Deoxy-2-(N⁶-trityladenin-3-yl)-3,5-di-O-trityl-α-D-arabinofuranosyl fluoride 
• 137964-98-8 [9-((2R,3S,4R,5R)-3-Fluoro-4-trityloxy-5-trityloxymethyl-tetrahydro-furan-2-yl)-9H-purin-6-yl]-trityl-amine 
• 137965-00-5 {(2R,3S,4S,5R)-5-Fluoro-4-[6-(trityl-amino)-purin-3-yl]-3-trityloxy-tetrahydro-furan-2-yl}-methanol 
• 137965-08-3 9-(3,5-Di-O-trityl-2-deoxy-D-erythro-pent-1-enofuranosyl)-N⁶-trityladenine 
• 137965-06-1 N⁶-triphenylmethyl-9-(3',5'-bis-O-triphenylmethyl-β-D-arabinofuranosyl)adenine 
• 137965-07-2 2'-Deoxy-2'-fluoro-3',5'-di-O-trityl-N⁶-trityladenosine 
• 20187-82-0 9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)adenine 
• 1172119-74-2 C₂₇H₃₄FN₇O₅ 
• 144924-99-2 N-(9-((2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-yl)benzamide 

Relevant academic research and scientific papers

INHIBITORS OF S-ADENOSYL-L-METHIONINE DECARBOXYLASE

Novel mechanism-based inhibitors of S-adenosyl-L-methionine decarboxylase are provided. These compounds of formula (1) inhibit the life cycle of trypanosomes, and are useful to treat subjects infected with African trypanosomes. The invention includes pharmaceutical compositions and methods of using the compounds of formula (1).