310888-64-3Relevant academic research and scientific papers
Stereoselective synthesis of C-glycosides from carboxylic acids: The tandem Tebbe-Claisen approach
Godage, H. Yasmin,Chambers, David J.,Evans, Graham R.,Fairbanks, Antony J.
, p. 3772 - 3786 (2007/10/03)
A variety of β- or α-C-glycosides may be readily accessed in an entirely stereoselective fashion from esters derived from the reaction of carboxylic acids and 3-hydroxy glycals, by way of a tandem reaction sequence of Tebbe methylenation and Claisen rearrangement. Though of wide scope, for example allowing the synthesis of 1-6 linked C-disaccharides, the methodology does not currently allow the synthesis of C-glycosyl α-amino acids.
Stereoselective synthesis of C-glycosides via Tebbe methylenation and Claisen rearrangement
Godage,Fairbanks
, p. 7589 - 7593 (2007/10/03)
A variety of β-C-glycosides may be readily accessed in a stereoselective fashion from 3-OH glycal esters, via the use of Tebbe methylenation and subsequent thermal Claisen rearrangement. The use of carbohydrate ester substrates allows the formation of β(1
