31127-54-5

Basic information

• Product Name: 2,3,4,4'-Tetrahydroxybenzophenone
• Synonyms: 4-(4-Hydroxybenzoyl)-1,2,3-trihydroxybenzene;2,3,4,4'-TETRAHYDROXYBENZOPHENONE;2,3,4,4-TETRAHYDROXYBENZOPHENONE;2,3,4,4'-THBP;2,3,4,4'-Tetrehydroxybenzophenone;(4-hydroxyphenyl)(2,3,4-trihydroxyphenyl) methanone;2,3,4,4'-Tetrahydroxybenzophenone(Bp-28);Methanone, (4-hydroxyphenyl)(2,3,4-trihydroxyphenyl)-
• CAS NO: 31127-54-5
• Molecular Formula: C₁₃H₁₀O₅
• Molecular Weight: 246.22
• Product Categories: RAW material for Photo Active Compounds;Industrial/Fine Chemicals;Aromatic Benzophenones & Derivatives (substituted)
• Mol File: 31127-54-5.mol
• Article Data: 5

Chemical Properties

• Melting Point: 199-204°C
• Boiling Point: 519 °C at 760 mmHg
• Flash Point: 281.7 °C
• Appearance: /
• Density: 1.526 g/cm³
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 7.38±0.40(Predicted)
• Water Solubility: 15.07g/L(24.99 oC)
• CAS DataBase Reference: 2,3,4,4'-Tetrahydroxybenzophenone(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3,4,4'-Tetrahydroxybenzophenone(31127-54-5)
• EPA Substance Registry System: 2,3,4,4'-Tetrahydroxybenzophenone(31127-54-5)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 31127-54-5(Hazardous Substances Data)

Usage

Chemical Properties

Yellow powder

Preparation

Preparation by benzoylation of pyrogallol with p-hydroxybenzoic acid in the presence of Amberlyst-15 in refluxing toluene for 21 h under azeotropical removal of water (86%).

Upstream product

• 100-66-3 methoxybenzene 
• 7169-07-5 3,4,5-(trimethoxy)benzoyl chloride 
• 619-57-8 p-hydroxybenzamide 
• 87-66-1 2-hydroxyresorcinol 
• 120-47-8 Ethyl 4-hydroxybenzoate 
• 28141-24-4 4-hydroxybenzoyl chloride 
• 610-02-6 2,3,4-trihydroxybenzoic acid 
• 108-95-2 phenol 
• 99-96-7 4-hydroxy-benzoic acid 

Relevant articles and documents

Production method of 2,3,4,4'-tetrahydroxy benzophenone

The invention discloses a production method of 2,3,4,4'-tetrahydroxy benzophenone.Uniformly mixing pyrogallic acid, p-hydroxybenzoic acid, water and functionalized magnetic silica gel loaded biimidazole ionic liquid in a reaction container, stirring, heat

Method for preparing 2,3,4,4' tetrahydroxy diphenyl ketone at normal pressure

The invention discloses a method for preparing 2,3,4,4' tetrahydroxy diphenyl ketone at normal pressure. An acylation reagent, pyrogallic acid, a catalyst and isoamyl alcohol are mixed in a reactor, inert gas is introduced, a reaction is carried out in th

Synthesis and biological evaluation of polyhydroxy benzophenone as mushroom tyrosinase inhibitors

A series of polyhydroxy benzophenone were synthesized and evaluated as mushroom tyrosinase inhibitors. The results demonstrated that most of the target compounds had remarkable inhibitory activities on mushroom tyrosinase. Among all these compounds, 2,3,4,3′,4′,5′-hexahydroxy-diphenylketone 10 was found to be the most potent tyrosinase inhibitor with IC50 value of 1.4 μM. In addition, the inhibition kinetics analyzed by Lineweaver-Burk plots revealed that such compounds were competitive inhibitors. These results suggested that such compounds might be utilized for the development of new candidate for treatment of dermatological disorders.