3115-55-7Relevant articles and documents
Enzymatic hydrolysis of β-lactam antibiotics at low pH in a two-phase "aqueous solution - Water-immiscible organic solvent" system
Chilov, Ghermes G.,Svedas, Vytas K.
, p. 699 - 707 (2007/10/03)
The application of the two-phase "aqueous solution - water-immiscible organic solvent" system is suggested not for effective biocatalytic synthesis, but for hydrolytic purposes. Enzymatic hydrolysis of benzylpenicillin and N-phenylacetamidodesacetoxycepha
Extractive deacylation of benzylpenicillin in aqueous two-phase systems
Andersson,Mattiasson,Hahn Hagerdal
, p. 749 - 753 (2007/10/02)
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Process for production of 6-aminopenicillanic acid or 7-aminocephalosporanic acid derivatives
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, (2008/06/13)
A derivative of 6-aminopenicillanic acid or 7-aminocephalosporanic acid is produced by a process which comprises chlorinating or brominating a 6-thioacylaminopenicillanic acid or 7-thioacylaminocephalosporanic acid compound to obtain a corresponding iminothiohalide compound, and then solvolyzing the iminothiohalide compound. The process is novel and industrially feasible for producing the amino compound, which is not accompanied by "reconversion reaction".