31167-90-5

Basic information

• Product Name: 3-chlorodihydrofuran-2(3H)-one
• Synonyms: 3-chlorodihydrofuran-2(3H)-one;3-Chloro-4,5-dihydrofuran-2(3H)-one
• CAS NO: 31167-90-5
• Molecular Formula: C₄H₅ClO₂
• Molecular Weight: 120.5343
• EINECS: 250-498-0
• Mol File: 31167-90-5.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 258.4°Cat760mmHg
• Flash Point: 139.5°C
• Appearance: /
• Density: 1.31g/cm³
• Vapor Pressure: 0.0138mmHg at 25°C
• Refractive Index: 1.462
• CAS DataBase Reference: 3-chlorodihydrofuran-2(3H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-chlorodihydrofuran-2(3H)-one(31167-90-5)
• EPA Substance Registry System: 3-chlorodihydrofuran-2(3H)-one(31167-90-5)

Safety Data

• Hazardous Substances Data: 31167-90-5(Hazardous Substances Data)

Usage

InChI:InChI=1/C4H5ClO2/c5-3-1-2-7-4(3)6/h3H,1-2H2

Upstream product

• 1927-25-9 DL-Homoserine 
• 160663-34-3 α-chloro-α-formyl-γ-butyrolactone 
• 123-54-6 acetylacetone 
• 18017-35-1 α,γ-dichlorobutyric acid 
• 96-48-0 4-butanolide 

Downstream Products

• 31145-62-7 3-m-tolyloxy-dihydro-furan-2-one 

Relevant articles and documents

Application of axial haloketone rule to lactones

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Preparation method of 3-aminomethyl tetrahydrofuran

The invention relates to a preparation method of 3-aminomethyl tetrahydrofuran. Specifically the invention relates to a method of preparing 3-aminomethyl tetrahydrofuran through reducing 3-cyanotetrahydrofuran. A novel synthesis technology is adopted; gamma-butyrolactone and a halogen simple substance X2 are taken as the raw materials to prepare 3-X-gamma-butyrolactone; then 3-X-gamma-butyrolactone is reduced by a reducing agent to obtain 2-X-1,4-butylene glycol; 2-X-1,4-butylene glycol is dehydrated by a dehydrating agent to obtain 3-X tetrahydrofuran; 3-X tetrahydrofuran is converted into 3-cyanotetrahydrofuran in the presence of a cyaniding catalyst, and finally 3-cyanotetrahydrofuran is converted into 3-aminomethyl tetrahydrofuran in the presence of a hydrogenation catalyst. The synthesis technology has the advantages of easily available raw materials, simple operation, mild reaction conditions, high yield and product purity, little environmental pollution, and low production cost, is suitable for industrial massive production, and has a wide application prospect.

Method for the Production of D,L-2-Hydroxy-4-Alkylthio Butyric Acid

The present invention relates to a process for preparing compounds of the formula (I) by reacting compounds of the formula (II) with thiolates (RS)nM. The present invention further relates to a process for preparing compounds of the formula (II) from γ-butyrolactone.