31168-29-3Relevant academic research and scientific papers
ANNOQUINONE-A, AN ANTIMICROBIAL AND CYTOTOXIC PRINCIPLE FROM ANNONA MONTANA
Wu, Tian-Shung,Jong, Ting-Ting,Tien, Hsien-Ju,Kuoh, Chang-Sheng,Furukawa, Hiroshi,Lee, Kuo-Hsiung
, p. 1623 - 1626 (1987)
A new naturally occuring phenanthrene-1,4-quinone, annoquinone-A, along with parietin (physcion) and β-sitostenone were isolated from the stem bark of Annona montana.The structure of annoquinone-A was elucidated by spectral methods and synthesis.Annoquinone-A demonstrated potent antimicrobial activity against Bacillus subtilis and Micrococcus luteus as well as cytotoxicity in the KB (ED50=0.16 μg/ml) tissue culture assay. β-Sitostenone also showed significant cytotoxicity.Key Word Index - Annona montana; Annonaceae; phenanthrene-1,4-quinone; annoquinone-A; anthraquinone; antibacterial activity; cytotoxicity.
