312325-74-9

Usage

Uses

Used in Pharmaceutical Industry:
2-(2-Bromopyridin-4-yl)acetonitrile is used as a key intermediate for the synthesis of various pharmaceutical compounds. Its unique structure and reactivity make it a valuable building block in the development of new drugs, contributing to the advancement of medicinal chemistry.
Used in Agrochemical Industry:
In the agrochemical sector, 2-(2-Bromopyridin-4-yl)acetonitrile serves as an essential intermediate in the production of agrochemicals. Its incorporation into the synthesis process aids in the creation of effective pesticides and other agricultural chemicals, enhancing crop protection and yield.
Used in Organic Synthesis:
2-(2-Bromopyridin-4-yl)acetonitrile is utilized as a versatile building block in organic synthesis. Its reactivity allows for the formation of a wide range of chemical compounds, making it a valuable component in the synthesis of various organic molecules for research and industrial applications.

InChI:InChI=1/C7H5BrN2/c8-7-5-6(1-3-9)2-4-10-7/h2,4-5H,1H2

Upstream product

• 58530-53-3 2,4-dibromopyridine 
• 75-05-8 acetonitrile 
• 118289-16-0 (2-bromopyridin-4-yl)methanol 
• 1295297-98-1 (2-bromopyridin-4-yl)methyl methanesulfonate 
• 4926-28-7 2-Bromo-4-picoline 
• 5815-08-7 tert-Butoxybis(dimethylamino)methane 

Downstream Products

• 1000188-61-3 5-amino-4-(2-bromopyridin-4-yl)-3-(4-fluorophenyl)isoxazole 
• 1279815-46-1 1-(2-bromopyridin-4-yl)-cyclopropanecarbonitrile 
• 1295298-11-1 1-(4-fluorophenyl)-1H-pyrazolo[3,4-c]pyridine-4-carboxylic acid [1-(2-bromopyridin-4-yl)cyclopropyl]amide 

Relevant academic research and scientific papers

INDAZOLE AND PYRAZOLOPYRIDINE COMPOUNDS AS CCR1 RECEPTOR ANTAGONISTS

Diclosed are CCRl receptor antagonists of the formula (I), wherein X is nitrogen or, C-R2; Ar1 is carbocycle, heteroaryl or heterocyclyl each optionally substituted by one to three Ra; Ar2 is carbocycle, heteroaryl or heterocyclyl, each optionally substituted by one to three Rb; Cyclic G is carbocycle, or heterocyclyl each optionally substituted by one to two R8; R1 is hydrogen, C1-6 alkyl or C 1-6 alkoxyC1-6 alkyl. Also disclosed are compositions, methods of making and using compounds of the formula (I).

HETEROCYCLIC COMPOUNDS AS CCR1 RECEPTOR ANTAGONISTS

Disclosed are CCR1 receptor antagonists of the formula (I) wherein Ar1, Ar2, R1-R3, X and L are disclosed herein. Also disclosed are compositions, methods of making and using compounds of the formula (I).

PYRIDYLISOXAZOLE DERIVATIVE

This invention offers isoxazole derivatives represented by the following formula (I) in which R1 and R2 each stands for hydrogen, lower alkyl, amino and the like; R3 stands for substituted or unsubstituted aryl or hetero a

Facile cyanomethylation of bromopyridines by nucleophilic substitution with lithioacetonitrile

Substituted bromopyridines undergo facile nucleophilic substitution with lithioacetonitrile under mild conditions to afford the corresponding cyanomethylated products.