312693-16-6 Usage
Uses
Used in Organic Synthesis:
3-Methoxybenzylzinc chloride is used as a reagent for the formation of carbon-carbon bonds, which is crucial in creating complex organic molecules. Its ability to form these bonds selectively and efficiently makes it a preferred choice in various organic synthesis processes.
Used in Pharmaceutical Synthesis:
In the pharmaceutical industry, 3-Methoxybenzylzinc chloride is used as a key intermediate in the synthesis of various pharmaceuticals. Its role in creating carbon-carbon bonds allows for the development of new and innovative drug molecules with potential therapeutic applications.
Used in Natural Product Synthesis:
3-Methoxybenzylzinc chloride is also utilized in the synthesis of natural products, which are often complex organic compounds derived from plants, animals, or microorganisms. Its ability to form carbon-carbon bonds is essential in replicating the intricate structures of these natural products for research and commercial purposes.
Used in Fine Chemicals Production:
In the production of fine chemicals, which are high-purity chemicals used in various industries, 3-Methoxybenzylzinc chloride serves as a valuable reagent. Its contribution to the formation of carbon-carbon bonds is vital for creating high-quality specialty chemicals used in applications such as fragrances, dyes, and agrochemicals.
Used in Grignard-Type Reactions:
3-Methoxybenzylzinc chloride is particularly useful in Grignard-type reactions, which are a class of chemical reactions that involve the formation of carbon-carbon bonds. Its application in these reactions contributes to the synthesis of a variety of organic compounds, showcasing its versatility and importance in organic chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 312693-16-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,1,2,6,9 and 3 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 312693-16:
(8*3)+(7*1)+(6*2)+(5*6)+(4*9)+(3*3)+(2*1)+(1*6)=126
126 % 10 = 6
So 312693-16-6 is a valid CAS Registry Number.
InChI:InChI=1/C8H9O.ClH.Zn/c1-7-4-3-5-8(6-7)9-2;;/h3-6H,1H2,2H3;1H;/q;;+1/p-1/rC8H9ClOZn/c1-10-8-4-2-3-7(5-8)6-11-9/h2-5H,6H2,1H3
312693-16-6Relevant academic research and scientific papers
Asymmetric Synthesis of Fluorinated Allenes by Rhodium-Catalyzed Enantioselective Alkylation/Defluorination of Propargyl Difluorides with Alkylzincs
Hayashi, Tamio,Ng, Jia Sheng
supporting information, p. 20771 - 20775 (2021/08/25)
The reaction of propargyl difluorides R1CF2C≡CR2 with alkylzincs R3ZnCl giving axially chiral fluorinated allenes R1FC=C=CR2R3 with high enantioselectivity (up to 99 % ee) was found to be catalyzed by a chiral diene/rhodium complex. A key step in the catalytic cycle is selective elimination of one of the enantiotopic fluorides at the β-position of an alkenyl-Rh intermediate, which is generated by regioselective addition of R3-Rh onto the triple bond of the starting difluorides.
