312947-24-3 Usage
Uses
Used in Pharmaceutical Research and Drug Development:
[(5-phenylthieno[2,3-d]pyrimidin-4-yl)thio]acetic acid is utilized as a key compound in medicinal chemistry research and drug development. Its unique structure and potential biological activity make it a promising candidate for the treatment of various diseases, including cancer and inflammation.
Used in Cancer Treatment:
In the field of oncology, [(5-phenylthieno[2,3-d]pyrimidin-4-yl)thio]acetic acid is explored as a therapeutic agent for the treatment of different types of cancer. Its specific mode of action and interaction with cellular targets are under investigation to determine its efficacy and potential synergistic effects when combined with conventional cancer treatments.
Used in Inflammation Management:
Additionally, [(5-phenylthieno[2,3-d]pyrimidin-4-yl)thio]acetic acid is studied for its potential role in managing inflammation. Its ability to modulate inflammatory pathways and reduce the associated symptoms could make it a valuable addition to the arsenal of anti-inflammatory drugs.
Used in Chemical Synthesis:
[(5-phenylthieno[2,3-d]pyrimidin-4-yl)thio]acetic acid is also employed as a building block or intermediate in the synthesis of more complex molecules with diverse applications, such as pharmaceuticals, agrochemicals, and materials science.
Check Digit Verification of cas no
The CAS Registry Mumber 312947-24-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,1,2,9,4 and 7 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 312947-24:
(8*3)+(7*1)+(6*2)+(5*9)+(4*4)+(3*7)+(2*2)+(1*4)=133
133 % 10 = 3
So 312947-24-3 is a valid CAS Registry Number.
312947-24-3Relevant academic research and scientific papers
Synthesis and biological evaluation of substituted (thieno[2,3-d]pyrimidin- 4-ylthio)carboxylic acids as inhibitors of human protein kinase CK2
Golub, Andriy G.,Bdzhola, Volodymyr G.,Briukhovetska, Nadiia V.,Balanda, Anatoliy O.,Kukharenko, Olexander P.,Kotey, Igor M.,Ostrynska, Olga V.,Yarmoluk, Sergiy M.
, p. 870 - 876 (2011/04/22)
A novel series of substituted (thieno[2,3-d]pyrimidin-4-ylthio)carboxylic acids has been synthesized and tested in vitro towards human protein kinase CK2. It was revealed that the most active compounds inhibiting CK2 are 3-{[5-(4-methylphenyl)thieno[2,3-d]pyrimidin-4-yl]thio}propanoic acid and 3-{[5-(4-ethoxyphenyl)thieno[2,3-d]pyrimidin-4-yl]thio}propanoic acid (IC 50 values are 0.1 μM and 0.125 μM, respectively). Structure-activity relationships of 28 tested thienopyrimidine derivatives have been studied and binding mode of this chemical class has been predicted. Evaluation of the inhibitors on seven protein kinases revealed considerable selectivity towards CK2.
